目的：分组研究不同前房深度(ACD)近视患者眼部参数与晶状体厚度(LT)的关系。

方法：横断面研究。选取2022-05/2024-05在我院屈光科行有晶状体眼后房型人工晶状体植入术的近视患者118例236眼。患者术前检查的眼部参数具体包括裸眼视力(UCVA)、主觉验光、最佳矫正视力(BCVA)、非接触式眼内压(IOP)、ACD、水平角膜直径(WTW)、水平沟到沟直径(STS_H)、垂直沟到沟直径(STS_V)及LT。使用Pentacam测量不含角膜厚度的ACD，并根据ACD不同将近视患者分为浅前房组(2.8 mm≤ACD≤3.2 mm)、中前房组(3.2 mm3.4 mm)3组。比较各组WTW、STS_H、STS_V及LT的差异，分析不同ACD分组下各参数间的相关性，采用多元线性回归分析LT与各参数的关系。

结果：中前房组与深前房组间LT比较无差异(P=1.00)，浅前房组与中前房组LT比较有差异(P<0.0167)； 而WTW、STS_H、STS_V在不同ACD组间比较均有差异(F=226.36、15.58、11.92，均P<0.01)，但重复进行两两比较后，差异各不相同。浅前房组及患者总体数据中LT仅与ACD存在较弱的负相关(r=-0.231，P<0.05； r=-0.222，P<0.01)，中前房组及深前房组中LT与眼部参数均不相关(均P>0.05)； 不同ACD组及患者总体数据中，WTW、STS_H、STS_V间均存在中度相关性(均P<0.01)； 而患者总体数据中ACD与WTW、STS_H、STS_V、LT间均存在较弱至低度的相关性(均P<0.01)。通过多元线性回归分析发现，仅浅前房组及总体数据存在有意义的自变量与LT呈线性相关性，其方程分别为：LT_S=5.492-0.167×WTW+0.267×STS_V-0.448×ACD； LT_T=3.884-0.303×ACD，其校正R²均较低，分别为0.141、0.056。

结论：不同ACD组中，LT与WTW、STS_H、STS_V间无相关性及线性关系； 浅前房组及患者总体数据中，LT与ACD存在较弱的负相关性，其校正R²较低，因此不同ACD下LT与眼部径线参数间均无线性关系。

METHODS:Cross-sectional study. A total of 118 myopic subjects(236 eyes)underwent posterior chamber phakic implantable collamer lens(Phakic-ICL)implantation in the refractive department of our hospital from May 2022 to May 2024 were selected. Ocular parameters examined before surgery included uncorrected visual acuity(UCVA), subjective refraction, best corrected visual acuity(BCVA), contactless intraocular pressure(IOP), ACD, white-to-white(WTW), horizontal sulcus-to-sulcus(STS_H), vertical sulcus-to-sulcus(STS_V), and LT. ACD without corneal thickness was measured by Pentacam, and subjects were divided into three groups: shallow anterior chamber group(2.8 mm≤ACD≤3.2 mm), middle anterior chamber group(3.2 mm3.4 mm). The differences in WTW, STS_H, STS_V, and LT among groups were compared, and the correlation between the above parameters under different ACD groups was analyzed, as well as the multiple linear regression analysis was used to research LT with the above ocular parameters.

RESULTS:There was no statistically significant difference in LT between the middle ACD group and the deep ACD group(P=1.00), while there were statistically significant differences in LT between shallow and middle ACD groups(P<0.0167); there were statistical significant differences in WTW, STS_H and STS_V among different ACD groups(F=226.36, 15.58, 11.92, all P<0.01), but the differences were varied after pairwise comparison. There was a weak negative correlation between LT and ACD only in the shallow ACD group and overall data of patients(r=-0.231, P<0.05; r=-0.222, P<0.01). There was no correlation in LT and ocular parameters between the middle ACD group and deep ACD group(all P>0.05); moderate correlations were discovered among WTW, STS_H and STS_V in different ACD groups and overall data(all P<0.01); in the overall data of patients, ACD had weak to low correlations with WTW, STS_H, STS_V and LT(all P<0.01). Through multiple linear regression analysis, it was found that only the shallow ACD group and the overall data had statistically significant independent variables that were linearly correlated with LT, and their equations were as follows: LT_S=5.492-0.167×WTW+0.267×STS_V-0.448×ACD; LT_T=3.884-0.303×ACD, the corrected R² of equations showed low values, revealed 0.141 and 0.056, respectively.

CONCLUSION:Among different ACD groups, there was no correlation or linear relationship between LT and WTW, STS_H and STS_V; in the shallow ACD group and the overall data, LT had a weak negative correlation with ACD, and its corrected R² was low. Therefore, there is no linear relationship between LT and ocular diameter parameters under different ACD.