保罗青光眼植入物治疗青光眼的初步观察

Preliminary observation of PAUL glaucoma implant in glaucoma treatment

摘要:

目的：初步评估保罗青光眼植入物在青光眼治疗中的有效性和安全性。

方法：回顾性分析2022-03/2023-01接受保罗青光眼植入物治疗的青光眼患者10例10眼的临床资料。至少随访12 mo，观察手术前后视力、眼压和抗青光眼用药数量等指标的变化。

结果：纳入患者末次随访时视力较术前无明显变化； 术前眼压19-60(中位数28)mmHg，末次随访时眼压为10-18(中位数14)mmHg。术前所有患者均需使用2-4种抗青光眼药物，末次随访时仅1例患者需使用。4例患者末次随访时角膜内皮细胞密度较术前明显下降，未发生角膜相关并发症。截至末次随访，10例患者均获得手术成功。

结论：保罗青光眼植入物具有显著的降眼压疗效，角膜内皮细胞损害可能是其存在的隐患。

Abstract:

AIM: To preliminarily assess the efficacy and safety of PAUL glaucoma implant in glaucoma management.

METHODS: Clinical data of 10 glaucoma patients(10 eyes)who treated with Paul's glaucoma implant from March 2022 to January 2023 were retrospectively analyzed. A follow-up of 12 mo was performed to observe changes in visual acuity, intraocular pressure, and number of anti-glaucoma medications before and after surgery.

RESULTS: Included patients had no significant change in visual acuity from preoperative to last follow-up; preoperative intraocular pressure was 19-60(median 28)mmHg, and it was 10-18(median 14)mmHg at last follow-up. All patients required two to four antiglaucoma medications preoperatively, and only 1 case needed medications at final follow-up. Four patients had a significant decrease in corneal endothelial cell density compared with the preoperative period, and no corneal-related complications occurred. At final follow-up, all 10 patients met surgical success criteria.

CONCLUSION: PAUL glaucoma implant has significant IOP lowering efficacy and that corneal endothelial cell damage may be a pitfall of its presence.