缝线引导GATT联合白内障超声乳化术治疗原发性开角型青光眼
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广西医疗卫生适宜技术开发与推广应用项目(No.S2021039,S201640); 广西科技计划项目(No.桂科AD19245193)


Suture guided gonioscopy-assisted transluminal trabeculotomy combined with phacoemulsification in the treatment of primary open angle glaucoma
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Guangxi Development and Application Project for Medical and Health Appropriate Technology(No.S2021039,S201640); Science and Technology Plan Project of Guangxi(No.AD19245193)

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    摘要:

    目的:探讨缝线引导GATT联合白内障超声乳化术治疗原发性开角型青光眼(POAG)的临床疗效。

    方法:选取2021-01/2022-07于我院行手术治疗的合并白内障的POAG患者84例84眼,随机分成两组,联合组43例43眼行缝线引导GATT联合白内障超声乳化术,单纯组41例41眼行缝线引导GATT术。随访3mo,比较两组患者手术成功率、眼压、局部使用降眼压药物种类、视力及术后并发症情况。

    结果:术后3mo,联合组和单纯组患者手术总成功率无显著差异(88% vs 85%,P>0.05)。两组患者术后1wk,1、3mo眼压水平、局部使用降眼压药物种类均较术前显著降低(均P<0.05),但两组间无显著差异(均P>0.05)。术后1wk,1、3mo联合组患者视力均显著优于单纯组(P<0.01)。随访期间,联合组患者前房出血、一过性高眼压发生率均显著低于单纯组(P<0.05)。

    结论:缝线引导GATT手术是否联合白内障超声乳化术均可有效治疗POAG,但缝线引导GATT联合白内障超声乳化术后前房出血、一过性高眼压发生率更低。

    Abstract:

    AIM: To investigate the clinical efficacy of suture-guided gonioscopy-assisted transluminal trabeculotomy(GATT)combined with phacoemulsification in the treatment of primary open angle glaucoma(POAG).

    METHODS: A total of 84 patients(84 eyes)with POAG and cataract who underwent surgery in our hospital from January 2021 to July 2022 were selected and randomly divided into two groups. There were 43 cases(43 eyes)in the combined group who underwent suture-guided GATT combined with phacoemulsification, and 41 cases(41 eyes)in the simple group who underwent suture-guided GATT. The two groups were followed up for 3mo to compare the surgical success rate, intraocular pressure, topical intraocular pressure-lowering drugs, visual acuity and postoperative complications.

    RESULTS: There was no significant difference in overall success rate between the combination and simple groups at 3 mo after surgery(88% vs. 85%, P>0.05). The intraocular pressure levels and topical intraocular pressure-lowering drugs at 1wk, 1 and 3mo after surgery in the two groups were significantly lower than those before surgery(all P<0.05), but there was no significant difference between the two groups(all P>0.05). The visual acuity at 1wk, 1 and 3mo after surgery of patients in the combined group was significantly better than that in the simple group(P<0.01). During the follow-up period, the incidence of anterior chamber hemorrhage and transient hypertension in the combined group was significantly lower than that in the simple group(P<0.05).

    CONCLUSION: Both suture-guided GATT combined with cataract phacoemulsification and suture-guided GATT are effective treatment for POAG, however, suture-guided GATT combined with phacoemulsification has a lower incidence of anterior chamber hemorrhage and transient ocular hypertension.

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钟珊,杨卉,何诗,等.缝线引导GATT联合白内障超声乳化术治疗原发性开角型青光眼.国际眼科杂志, 2023,23(5):804-807.

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  • 收稿日期:2022-11-14
  • 最后修改日期:2023-04-13
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  • 在线发布日期: 2023-04-27
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