目的：比较翼状胬肉切除分别联合干性羊膜移植、湿性羊膜移植治疗原发性翼状胬肉的效果及术后恢复情况。

方法：回顾性研究。选取2020-05/10于我院就诊的原发性翼状胬肉患者120例137眼，按照治疗方式分为两组，A组60例67眼采取翼状胬肉切除联合干性羊膜移植治疗方案，B组60例70眼采取翼状胬肉切除联合湿性羊膜移植治疗方案。比较两组患者手术前后泪液分泌功能(SⅠt)、泪膜破裂时间(BUT)及视力的变化，术后疼痛评分、眼部充血及水肿消退时间、创面愈合时间、并发症及复发情况。

结果：两组患者手术前后SⅠt无显著差异(P>0.05)； 两组患者术前、术后7d BUT无显著差异(P>0.05)，但B组术后30、90d BUT明显长于A组(均P<0.01)； 两组患者术后疼痛评分无组间差异(P>0.05)； 两组患者术前、术后30d裸眼视力与最佳矫正视力组间均无显著差异(P>0.05)，但术后30d UCVA均较术前明显改善(P<0.001)； B组患者术后眼部充血消退时间、水肿消退时间及创面愈合时间均明显短于A组(P<0.05)。随访1a，两组患者并发症总发生率无显著差异(11.9% vs 8.6%，P>0.05)，但B组患者复发率明显低于A组(2.9% vs 13.4%，P<0.05)。

结论：与翼状胬肉切除联合干性羊膜移植相比，翼状胬肉切除联合湿性羊膜移植治疗原发性翼状胬肉疗效更好，患者术后愈合更快，复发率更低。

METHODS: A retrospective study was conducted on 120 patients(137 eyes)with primary pterygium who were treated in our hospital from May to October 2020. The subjects were divided into two groups according to different treatments. The 60 patients of group A(67 eyes)were treated with pterygium resection combined with dry amniotic membrane transplantation, while the 60 patients of group B(70 eyes)were treated with pterygium resection combined with hydrated amniotic membrane transplantation. Comparison was made between the two groups in terms of the changes in Schirmer test I(SⅠt), tear film break-up time(BUT)and vision before and after operation.Moreover, the postoperative pain score, regression time of ocular hyperemia and edema, wound healing time, complications and recurrence rate were compared.

RESULTS: SⅠt in the two groups showed no significant difference before and after operation(P>0.05). BUT of the two groups showed no significant difference before operation and on 7d after operation(P>0.05). BUT of group B was significantly longer than that of group A on 30 and 90d after operation(all P<0.01). There was no significant difference in pain score between the two groups after operation(P>0.05). There was no significant difference between the groups in terms of the uncorrected visual acuity and the best corrected visual acuity before operation and on 30d after operation(P>0.05). The UCVA of the two groups was significantly improved on 30d after operation(P<0.001). The regression time of ocular hyperemia and edema and wound healing time in group B were significantly shorter than those in group A(P<0.05). The total incidence of complications during 1a of follow-up showed no significant difference between the two groups(11.9% vs 8.6%, P>0.05), but the recurrence rate in group B was significantly lower than that in group A(2.9% vs 13.4%, P<0.05).

CONCLUSION: Pterygium resection combined with hydrated amniotic membrane transplantation is more effective than pterygium resection combined with dry amniotic membrane transplantation in the treatment of primary pterygium. Meanwhile, the patients heal faster after surgery, and the recurrence rate is lower.