[关键词]
[摘要]
目的：探讨系统性免疫指数(SII)、中性粒细胞/淋巴细胞比值(NLR)、血小板/淋巴细胞比值(PLR)在视网膜静脉阻塞患者(RVO)中的表达情况及检测价值。
方法：选取2019-08/2021-08在大连市第三人民医院就诊的CRVO患者57例、BRVO患者88例，正常人89例作为对照。比较各组血细胞计数及SII、NLR、PLR水平。利用受试者工作特征曲线(ROC)判断SII在RVO发生中的预测价值。
结果：CRVO组和BRVO组中性粒细胞、白细胞计数和NLR、SII均高于对照组，且有显著性差异(均P<0.05)。
结论：RVO患者SII与正常人存在显著差异，SII可能作为RVO诊断或病程进展监测的一个有潜力的临床评价指标。
[Key word]
[Abstract]
AIM: To evaluate the expression of systemic immune-inflammation index(SII),neutrophil/lymphocyte ratio(NLR)and platelet/lymphocyte ratio(PLR)and their value in patients with retinal vein occlusion(RVO).
METHODS: A total of 57 patients with CRVO,88 patients with BRVO and 89 normal subjects were recruited in Dalian No.3 People's Hospital from August 2019 to August 2021. Blood cell counts and SII,NLR,and PLR levels were compared. Receiver operating characteristic(ROC)curve was used to determine the predictive value of SII in the occurrence of RVO.
RESULTS:Neutrophil,white blood cell counts, NLR and SII were higher in the CRVO and BRVO groups than in the control group, and there was a significant difference(all P<0.05).
CONCLUSION: The SII value of RVO patients was significantly different from normal subjects,and SII may be a potential clinical evaluation index for RVO diagnosis or disease progression monitoring.
[中图分类号]
[基金项目]
大连市科技创新基金项目(No.2020JJ27SN094)
