目的：探究丹参注射液离子导入治疗视网膜静脉阻塞(RVO)的疗效。

方法：回顾性分析我院2020-01/2021-12收治的RVO患者90例90眼的临床资料，依据治疗方式进行分组，对照组患者38例38眼采取静脉滴注血栓通+口服复方血栓通胶囊+肠溶阿司匹林治疗，观察组患者52例52眼在此基础上行丹参注射液离子导入治疗，治疗时间均为3mo。对比两组患者临床疗效、治疗前后最佳矫正视力、视网膜情况及血液流变学指标(全血低切黏度、血浆纤维蛋白原)变化情况。

结果：治疗后3mo，观察组患者临床总有效率显著高于对照组(87% vs 58%，P<0.05)，两组患者最佳矫正视力均较治疗前改善且观察组优于对照组(均P<0.05)，两组患者视网膜静脉循环时间、视网膜静脉相对直径、视网膜相对出血面积均较治疗前降低且观察组低于对照组(均P<0.05)，两组患者全血低切黏度、纤维蛋白原水平均较治疗前降低且观察组低于对照组(均P<0.05)。

结论：RVO患者加用丹参注射液离子导入治疗疗效显著，能够有效改善患者视力并治疗眼底病变，改善血流异常情况。

METHODS: The clinical data of 90 patients(90 eyes)with RVO treated in our hospital from January 2020 to December 2021 were analyzed retrospectively, and they were divided into control group and observation group according to treatment methods. A total of 38 patients(38 eyes)in the control group were treated with intravenous Xueshuantong+oral compound Xueshuantong capsule+enteric-coated aspirin, and 52 patients(52 eyes)in the observation group were treated with Danshen injection iontophoresis on this basis. The treatment time of the two groups was 3mo. The clinical efficacy, best corrected visual acuity, retinal condition and hemorheological indexes(whole blood low shear viscosity, fibrinogen)were compared between the two groups before and after treatment.

RESULTS: The total effective rate of the observation group was significantly higher than that in the control group(87% vs 58%,P<0.05)at 3mo after treatment. The best corrected visual acuity in both groups was better than that before treatment, and the observation group was better than the control group(all P<0.05).The circulation time of retinal vein, the relative diameter of retinal vein and the relative area of retinal hemorrhage in the observation group were lower than those before treatment,and the observation group was lower than the control group(all P<0.05). The whole blood low shear viscosity and fibrinogen levels in the two groups were lower than those before treatment, and the observation group was lower than those in the control group(all P<0.05).

CONCLUSION: Danshen injection iontophoresis is effective in the treatment of patients with RVO, which can effectively improve the visual acuity, treat fundus lesions and improve the abnormal blood flow.