[关键词]
[摘要]
目的:通过增强深度成像光学相干断层扫描(EDI-OCT)技术比较远视性弱视与同龄正常儿童脉络膜结构的差异。
方法:选取2021-01/12就诊于我院的远视性弱视儿童35例50眼纳入弱视组,选取同期就诊一般资料相匹配的健康儿童30例51眼纳入对照组,均进行EDI-OCT检查,测量脉络膜厚度(CT),并对图像进行处理后获取总脉络膜面积(TCA)、血管腔面积(LA)、基质面积(SA)、脉络膜血管指数(CVI)。
结果:弱视组各区域TCA(下方除外)、SA(外环下方除外)、LA与CT(下方、颞侧除外)均明显大于对照组(P<0.05); 除外环颞侧外,两组各区域CVI无明显差异(P>0.05); 除鼻侧外,不同远视程度弱视儿童CT无明显差异(P>0.05)。
结论:远视性弱视存在脉络膜结构异常,随着远视度数增加,TCA、LA、SA有增大趋势,脉络膜结构改变与远视性弱视有关。
[Key word]
[Abstract]
AIM: To compare the differences in choroidal structure between hyperopic amblyopia and normal children of the same age by the enhanced depth imaging optical coherence tomography(EDI-OCT)technique.
METHODS: There were 35 cases in 50 eyes of children with hyperopic amblyopia visiting our hospital in January 2021 to December 2021 selected in the amblyopic group, and 30 cases in 51 eyes of healthy children who matched general data in the same period were selected in the control group. EDI-OCT examination was performed to measure the choroidal thickness(CT). After image processing, the total choroidal area(TCA), luminal area(LA), stromal area(SA)and choroidal vascularity index(CVI)were obtained.
RESULTS: TCA(except inferior quadrant), SA(except inferior quadrant of the outer ring), LA and CT(except inferior and temporal quadrant )in the amblyopic group of each area were significantly larger than that in the control group(P<0.05), and there was no significant difference in CVI between the two groups except the temporal quadrant of the outer ring(P>0.05). There was no significant difference in CT for all degrees of hyperopic amblyopia, with the exception of the nasal quadrant(P>0.05).
CONCLUSION: Hyperopic amblyopia is accompanied with abnormal choroidal structure. As the degree of hyperopia increases, TCA, LA and SA exhibit increasing trends. The changes in choroidal structure are presumed to be related to hyperopic amblyopia.
[中图分类号]
[基金项目]
广西壮族自治区卫生健康委员会科研课题(No.Z20211495)