方法：纳入2020-12/2021-03我院斜弱视门诊受检者，同一天用基于GMPE模块OCT与FCP两种方法测量客观眼球旋转度。FCP使用Adobe Photoshop软件手动定位测量黄斑中心凹-视盘中心夹角度数(FDA)，基于GMPE模块OCT软件自动定位黄斑和视盘中心测量FDA。

结果：纳入55例受检者，OCT测量FDA分别为右-6.6°±4.5°和左-8.8°±4.7°，FCP测量FDA分别为右-6.6°±4.7°和左-8.4°±4.1°，两种方法测量结果无差异(P_右眼=0.90，P_左眼=0.08)。外斜视患者OCT测量FDA分别为右-5.8°±4.9°和左-9.1°±4.5°，FCP测量FDA分别为右-5.7°±5.0°和左-8.6°±4.3°(P_右眼=0.75，P_左眼=0.15)。类似地，内斜视患者OCT测量FDA分别为右-9.0°±7.3°和左-11.3°±3.5°，而FCP测量FDA分别为右-10.0°±7.0°和左-10.1°±2.8°(P_右眼=0.21，P_左眼=0.10)，两种测量方法在内外斜视患者中均无差异(P>0.05)。Pearson检验及Bland-Altman分析两种方法的结果高度相关一致(r_右眼=0.93，r_左眼=0.94，均P<0.01)。

结论：基于GMPE模块OCT可用于客观眼球旋转度的测量，且可信度及重复度高，临床有望替代眼底彩色照相法。

METHODS: Patients were enrolled in our strabismus clinic from December 2020 to March 2021, and the objective ocular torsion of the eyes was measured by both GMPE module-based OCT and FCP on the same day. FCP was used to measure the fovea-disc angle(FDA)manually by using the Adobe Photoshop software, while the GMPE module-based OCT software positioned automatically the macula and the center of the optic disc to measure the FDA.

RESULTS: Fifty-five patients were included, the FDA measured by OCT was -6.6°±4.5° in the right eye and -8.8°±4.7° in the left eye, respectively; The FDA measured by FCP was -6.6°±4.7° in the right eye and -8.4°±4.1° in the left eye, respectively, with no statistically significant difference between the results of the two methods(P_{right eye}=0.90, P_{left eye}=0.08). In patients with exotropia, the FDA measured by OCT was -5.8°±4.9° in the right eye and -9.1°±4.5° in the left eye, respectively, the FDA measured by FCP was -5.7°±5.0° in the right eye and -8.6°±4.3° in the left eye, respectively,(P_{right eye}=0.75, P_{left eye}=0.15). Similarly, the patients with esotropia, the FDA measured by OCT was -9.0°±7.3° in the right eye and -11.3°±3.5° in the left eye, respectively, while the FDA measured by FCP was -10.0°±7.0° in the right and -10.1°±2.8° in the left eye(P_{right eye}=0.21, P_{left eye}=0.10), respectively. There were no significant differences between the two methods in patients with esotropia or exotropia(P>0.05). The results of both Pearson test and Bland-Altman analysis were highly correlated(r_{right eye}=0.93, r_{left eye}=0.94, P<0.01).

CONCLUSION: GMPE module-based OCT can be used for objective ocular torsion measurement with high reliability and reproducibility, and is a promising clinical alternative to the fundus color photographic method.