结膜印迹细胞学检查在过敏性结膜炎诊断中的价值

Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis

摘要:

目的：探讨结膜印迹细胞学(CIC)检查在过敏性结膜炎(AC)诊断中的价值。

方法：采用病例对照研究。将2021-01/02于我科就诊临床诊断为AC的患者40例80眼纳入研究，正常对照组40例80眼，均行双眼上睑CIC检查，观察各组结膜嗜酸性粒细胞的形态和数量，并进行Tseng分级。比较两组结果的差异，分析AC组患者中性别、年龄、病程对CIC检查嗜酸性粒细胞结果的影响。

结果：AC患者上睑CIC检查嗜酸性粒细胞阳性率明显高于正常对照组(χ²=57.744，P<0.001)； 其Tseng分级等级亦高于正常对照组(Z=-2.453，P<0.05)。性别、年龄、病程对AC组患者CIC检查嗜酸性粒细胞结果没有显著影响(均P>0.05)。

结论：CIC检查简单易行，结果客观精确，在AC的诊断中具有良好的应用价值。

Abstract:

AIM: To investigate the value of conjunctival impression cytology(CIC)in the diagnosis of allergic conjunctivitis(AC).

METHODS: A case-control study. Forty patients(80 eyes)who were clinically diagnosed with AC in our department from January to February 2021 were included in the study,and 40 normal controls(80 eyes)were enrolled too. All subjects underwent double upper palpebral CIC examinations. Observed the morphology and number of conjunctival eosinophils and carried out Tseng classification in each group. To Compare the differences between the results of the two groups and analyze the effects of gender, age and course of disease on the results of CIC eosinophil examination in AC group.

RESULTS: The positive rate of eosinophils in the upper palpebral CIC examination of AC patients was significantly higher than that of the normal control group(χ²=57.744, P<0.001); The Tseng grade of AC patients was also higher than that of the normal control group(Z=-2.453, P<0.05). Gender, age and course of disease had no significant effect on the results of CIC eosinophils in AC group(all P >0.05).

CONCLUSION: CIC examination is simple, and the result is objective and accurate. It has good application value in the diagnosis of AC.