方法：回顾性研究。选择2018-01/2019-09期间我院眼科收治的原发性翼状胬肉患者126例126眼为研究对象。根据患者手术方式分为观察组(无缝线自体结膜移植组，64例64眼)及对照组(缝线手术组，62例62眼)。对比两组患者手术时间、术后伤口愈合时间及眼部刺激症状、泪膜破裂时间和术后复发情况。

结果：观察组患者手术时间显著短于对照组，比较有差异(t=6.19，P<0.01)； 观察组患者术后结膜愈合时间显著短于对照组，比较有差异(t=12.82，P<0.01)，刺激症状发生率显著低于对照组，比较有差异(χ²=6.46，P=0.01)。除了术前两组患者泪膜破裂的比较无差异(t=-0.033，P>0.05)外，不同时间点的比较和术后两组间的比较均有统计学意义(均P<0.05)。观察组患者术后6、12mo均无复发，对照组6、12mo分别有1眼及2眼复发，两组术后复发率比较无差异(P>0.05)。

结论：翼状胬肉切除联合无缝线自体结膜移植术对翼状胬肉具有明确疗效，降低了术后刺激症状的发生率，缩短了手术的时间并有助于促进术后结膜愈合，具有良好的可及性。

METHODS: Retrospective study. A total of 126 patients(126 eyes)with primary pterygium treated in the ophthalmology department of our hospital during 2018-01/2019-09 were selected as subjects. According to the mode of operation, the patients were divided into observation group(64 eyes, 64 cases in seamless autologous conjunctival transplantation group)and control group(62 eyes, 62 cases in suture group). The operation time, postoperative wound healing time, ocular irritation symptoms, tear film rupture time and postoperative recurrence were compared between the two groups.

RESULTS: The operation time of the patients in the observation group was significantly shorter than that in the control group(t=6.19, P<0.01); The conjunctival healing time in the observation group was significantly shorter than that in the control group(t=12.82, P<0.01). The incidence of irritation symptoms in the control group was significantly lower than that in the control group(χ²=6.46, P=0.01). Except that there was no difference in the comparison of tear film rupture between the two groups before operation(t= -0.033, P>0.05), the comparison at different time points and the comparison between the two groups after operation were statistically significant(all P<0.05).There was no recurrence at 6 and 12mo in the observation group, but 1 eye and 2 eyes in the control group at 6 and 12mo, respectively. There was no significant difference in postoperative recurrence rate between the two groups(P >0.05).

CONCLUSION: Pterygium excision combined with seamless autologous conjunctival transplantation has a definite effect on pterygium, reduces the incidence of postoperative irritation symptoms, shortens the operation time and helps to promote postoperative conjunctival healing.