目的：探讨影响低中度近视儿童中心凹脉络膜厚度(SFCT)的相关因素。

方法：横断面研究。选择2020-10/12在徐州医科大学附属徐州市立医院眼科就诊的6～12岁近视儿童，按睫状肌麻痹验光所得等效球镜度(SER)纳入-0.75～-3.00D的低度近视患者60例60眼，-3.25～-6.00D的中度近视患者50例50眼，测量其SFCT、中心凹视网膜厚度(SFRT)、眼轴长度(AL)、眼调节参数，调查其年龄、性别、身高、体质量、父母近视情况，分析SFCT与各参数的关系。

结果：低、中度近视组SFCT分别为273.30±44.93、237.16±48.56μm(P<0.01)，Pearson相关分析得出SFCT与SER、AL、身高均有相关性(r=0.35、-0.45、-0.19，均P<0.05)，与其他因素均无相关性(均P>0.05)，多重线性回归显示SFCT随着AL的增长而变薄(B=-19.87，P<0.01)。

结论：低中度近视儿童SFCT与SER、AL、身高均有关，其中AL是影响SFCT的最主要因素，与其他因素关系不明显。

METHODS: A cross-sectional study. We selected children aged 6-12 who were diagnosed as myopia in the Department of Ophthalmology of the Affiliated Xuzhou Municipal Hospital of Xuzhou Medical University from October to December 2020, according to the spherical equivalent refraction(SER), 60 patients(60 eyes)with low myopia of -0.75 to -3.00D and 50 patients(50 eyes)with moderate myopia of -3.25 to -6.00D, which was obtained by cycloplegic refraction. All participants conducted ophthalmic examination, including measurements of SFCT, subfoveal retinal thickness(SFRT), axial length(AL), and parameters of ocular accommodation. Children's age, sex, parental myopia, height and weight were collected. The relationship between SFCT and various factors was investigated.

RESULTS: The average SFCT of the low and moderate myopia were 273.30±44.93 and 237.16±48.56μm(P<0.01), respectively. Pearson's correlation analysis showed that SFCT was statistically related to SER, AL and height(r=0.35, -0.45, -0.19, all P<0.05), and no statistical correlation with other factors(all P>0.05). Multiple linear regression showed that SFCT became thinner as AL became longer(B= -19.87, P<0.01).

CONCLUSION:SFCT in children with low to moderate myopia was statistically related to SER, AL and height, but it was not notably related to other factors. AL was the most significant factor affecting SFCT.