糖尿病性视网膜病变超广角荧光素眼底血管造影与标准7视野检查结果的对比分析

Comparative analysis of ultra-wide-field fluorescein angiography and standard 7-field imaging in diabetic retinopathy

摘要:

目的：对比分析糖尿病性视网膜病变(DR)超广角荧光素眼底血管造影与标准7视野检查结果，以期为DR的早期诊治提供理论依据。

方法：回顾性临床分析，收集2018-06/2020-06唐山市眼科医院诊治的120例DR患者临床资料，患者均接受超广角荧光素眼底血管造影与标准7视野检查，以眼底检查结果为金标准，评估超广角荧光素眼底血管造影与标准7视野检查在DR鉴别诊断中的价值。眼底病变特征的异同以及对DR分期评估价值。

结果：超广角荧光素眼底血管造影观察DR视网膜可视区面积、视网膜NP区面积、视网膜NV区面积、全视网膜激光光凝区面积、黄斑区拱环结构改变较标准7视野的明显高(P<0.05)，取图平均时间明显短于标准7视野检查(P<0.05)。超广角荧光素眼底血管造影检查结果对DR病情程度正确检出率为94.8%(165/174)，明显高于标准7视野的87.4%(152/174)(P<0.05)。

结论：超广角荧光素眼底血管造影技术在DR诊断中，在检查时间和检查空间方面较标准7视野检查更具优势，且前者更利于DR患者黄斑区、视盘区病变的检出，此外超广角荧光素眼底血管造影技术更利于DR患者病情程度的判断，可为DR的早期诊治提供更多参考。

Abstract:

AIM:To comparatively analyze the results of ultra-wide-field fluorescein angiography and standard 7-field imaging in diabetic retinopathy(DR), so as to provide a basis for early diagnosis and treatment of the disease.

METHODS: A retrospective study was conducted. The clinical data of 120 patients with DR admitted to Tangshan Eye Hospital between June 2018 and June 2020 were collected. All patients were subjected to ultra-wide-field fluorescein angiography and standard 7-field imaging. Taking fundus examination results as the golden standard, the value of the two methods in differential diagnosis of fundus lesions and staging of DR was analyzed.

RESULTS: Compared with standard 7-field imaging, the retinal view area, retinal non-perfusion(NP)area, retinal neovascularization(NV)area, panretinal laser photocoagulation area and structure changes of macular arch observed by ultra-wide-field fluorescein angiography were significantly larger(P<0.05), and the graph obtaining time was significantly shorter(P<0.05). The accurate detection rate of DR by ultra-wide-field fluorescein angiography was 94.8%(165/174), significantly higher than 87.4%(152/174)by standard 7-field imaging(P<0.05).

CONCLUSION: Ultra-wide-field fluorescein angiography has more advantages over standard 7-field imaging in the diagnosis of DR, especially in the time and space of examination. Besides, the former can better display macular and optic disc lesions, which is conducive to evaluation of DR, thereby providing more reference for early diagnosis and treatment of DR.