房水流出通路结构及功能显像的研究进展

Advances in the structure and function imaging of aqueous humor outflow

摘要:

房水作为重要眼内容物之一，一直处于动态循环中，若房水流出通路(AHO)中的任一部位受阻，都将导致眼压升高，并伴随青光眼的发生，进而出现视神经损伤，严重影响视功能。而开角型青光眼患者的房角呈开放状态，其眼压升高是房水流出阻力增加所致，因此，直观地观察AHO的结构，评价其功能变化，有助于我们更清晰地了解AHO的阻力所在，进一步阐明开角型青光眼的发病机制。目前对于AHO的显像技术包括光学相干断层扫描(OCT)以及AHO造影术等。本文将就AHO结构及功能显像的研究进展做一综述。

Abstract:

As one of the important contents of eyes, aqueous humor is always in dynamic circulation. When any part of the outflow is blocked, the aqueous humor outflow(AHO)circulation will break down, and followed by the increase of intraocular pressure, the damaged visual function, and the optic nerve injury. At last, the glaucoma occurs. Therefore, it can promote to locate the blocked part by observing the structure of the AHO and evaluating its function state, so as to clarify the pathogenesis of primary open angle glaucoma. Current imaging techniques for AHO pathway include optical coherence tomography(OCT)and angiography of outflow. This article will review the research progress of structure and function imaging of AHO.