目的：评价基于扫频光相干断层扫描(SS-OCT)技术的IOL Master 700生物测量仪测量白内障眼球生物参数的重复性，以及与部分相干光干涉生物测量仪IOL Master 500测量眼轴长度(AL)的一致性和检出率。

方法：采用横断面研究方法，共纳入2018-07/09门诊就诊的白内障患者133例225眼进行研究。由同一位经验丰富的检查者分别用IOL Master 700和IOL Master 500测量白内障患者眼球生物参数3次，记录AL、角膜曲率(K)、前房深度(ACD)、晶状体厚度(LT)、中央角膜厚度(CCT)、白到白角膜直径(WTW)。

结果：IOL Master 700测量白内障患者AL、K_m、K₁、K₂、ACD、LT、CCT、WTW的组内标准差(S_w)分别为0.027mm、0.112、0.148、0.162D、0.015、0.010mm、2.355μm、0.134mm，相对变异系数(CoV)为0.115%～1.162%，组内相关系数(ICC)≥0.923，其中AL的ICC最大为1.000，所有参数均有较高的重复性。IOL Master 700与IOL Master 500测量的AL分别为23.805±2.162、23.782±2.162mm，二者差值为0.023±0.010mm(t=33.645，P<0.001)； 95%一致性限(95%LoA)为0.003～0.043mm，两仪器测量的AL呈高度正相关(r=1.000，P<0.001)，一致性较好。IOL Master 700的AL检出率为93.8%(211/225)，IOL Master 500为87.6%(197/225)(χ²=5.147，P=0.023)。

结论：IOL Master 700测量白内障患者眼球生物参数AL、K_m、K₁、K₂、ACD、LT、CCT、WTW均有较高的重复性，其中AL重复性最好； 与IOL Master 500测量AL参数有较好一致性，但IOL Master 700对混浊严重及后囊下白内障AL检出率更高。

METHODS:A total of 225 eyes of 133 cataract patients were included in this cross-sectional study from July to September 2018. Ocular biometric parameters including AL, keratometry(K), anterior chamber depth(ACD), lens thickness(LT), central corneal thickness(CCT)and white to white(WTW)were measured for each participant by both IOL Master 700 and IOL Master 500.

RESULTS: The IOL Master 700 measured S_w of AL, K_m, K₁, K₂, ACD, LT, CCT, WTW in cataract patients were 0.027mm, 0.112D, 0.148D, 0.162D, 0.015mm, 0.010mm, 2.355μm and 0.134mm, CoV was 0.115%-1.162%, ICC≥0.923, the maximum ICC of AL is 1.000, and all measurements had high repeatability. The AL measured by IOL Master 700 and IOL Master 500 were(23.805±2.162)mm and(23.782±2.162)mm respectively, the difference was statistically significant(t=33.645, P<0.001). However, the 95% LoA was 0.003mm-0.043mm, and the AL measured by the two biometers was significantly correlated(r=1.000, P<0.001)with good agreement. The AL detection rates were 93.8%(211/225)for IOL Master 700 and 87.6%(197/225)for IOL Master 500, the difference was statistically significant(χ²=5.147, P=0.023).

CONCLUSION: IOL Master 700 demonstrates excellent repeatability in ocular biometric measurements including AL, K_m, K₁, K₂, ACD, LT, CCT and WTW for cataract patients, especially in AL measurement. IOL Master 700 is in good agreement with IOL Master 500 in measuring AL, however the IOL Master 700 has a higher detection rate for AL in patients with severe opacity and subcapsular opacity in their lens.