Amblyopia is the leading cause of visual impairment in children. It is also one of the main causes of monocular vision loss in adults. It is effectively treated using correct treatment when initiated during the sensitive period of visual development. Historically, patching or other means of penalization following refractive correction has been the main treatment for amblyopia. With the advancing of exploration on the neural mechanism of amblyopia, binocular treatment has been proposed as an innovative method for the treatment of amblyopia. Different forms of binocular treatment were reported by researchers. This review will focus on the application and progress of binocular treatment in amblyopia.