目的：比较扫频光相干断层扫描生物测量仪OA-2000与部分相干光干涉生物测量仪IOL Master 500测量白内障患者的AL的检出率和AL测量值的一致性，并评价OA-2000测量白内障患者眼球生物参数眼轴长度(AL)、角膜曲率(K)、前房深度(ACD)、晶状体厚度(LT)、中央角膜厚度(CCT)、瞳孔直径(PD)和白到白(WTW)的重复性。

方法：采用横断面研究方法。连续纳入2018-07/09本院眼科门诊就诊的白内障患者166例270眼，由同一位操作者先进行IOL Master 500测量AL并记录结果，随后进行OA-2000对AL、K、ACD、LT、CCT、PD、WTW数据测量。

结果：IOL Master 500 AL检出率为86.3%(233/270)； OA-2000检出率为97.0%(262/270)。两设备测量AL差值的范围为0.007±0.129mm，测量AL的95%LoA范围为-0.24～0.26mm。OA-2000在测量白内障患者眼球生物学参数中，除PD和WTW外，余参数如AL、ACD、K(2.5mm和3mm直径)、LT、CCT具有很好的重复性。

结论：OA-2000与IOL Master 500相比，对白内障患者AL测量的一致性很好，但OA-2000对AL的检出率更高。OA-2000不仅对于白内障患者AL、ACD、K、LT、CCT眼球生物学参数测量具有高重复性，并且对于混浊程度较重及后囊下混浊的白内障的AL测量更具优势。

METHODS: A cross-sectional study of 270 cataract eyes was implemented in the ophthalmic outpatient department from July to September 2018. Ocular biometric measurements including AL, keratometry readings(K), anterior chamber depth(ACD), lens thickness(LT), central corneal thickness(CCT), pupil diameter(PD)and white to white(WTW)were performed using OA-2000 and IOL Master 500. The detection rates of AL were calculated and compared between the two devices.

RESULTS: AL detection rates of 86.3%(233/270)and 97.0%(262/270)were found by IOL Master 500 and OA-2000 respectively. The mean difference in the measured AL by the two devices was(0.007±0.129)mm, and the 95% limits of agreement(95%LoA)of AL was 0.01(-0.24 to 0.26)mm. OA-2000 demonstrated good repeatability in measuring AL, ACD, K(2.5mm and 3mm pupil diameter), LT and CCT, but not in measuring PD and WTW.

CONCLUSION: Both OA-2000 and IOL Master 500 showed good agreement in AL measurement in cataract patients. However, compared with IOL Master 500, OA-2000 has a higher detection rate of AL. OA-2000 not only demonstrates excellent repeatability in ocular biometric measurements including AL, ACD, K, LT and CCT, but also more advantageous for the AL measurement of cataract with heavy lens opacity and subcapsular opacity.