[关键词]
[摘要]
铜绿假单胞菌性角膜炎是临床上常见的角膜炎之一,其起病急、发展迅速,并且治疗棘手。若未及时治疗,极易形成角膜溃疡,严重时可致盲。为增加有效治疗的手段,深入研究其发病机制有重要意义。本文就铜绿假单胞菌的致病性与宿主的免疫反应在铜绿假单胞菌性角膜炎的发病机制中所起的作用进行了概述,以期为其治疗的新思路提供理论依据。
[Key word]
[Abstract]
Pseudomonas aeruginosa keratitis can be described as one of the most common keratitis in clinical practice. It is characterized by an acute onset, fast development and hard to be treated entirely. Once failed to get prompt treatment, it would cause corneal ulcer, in an extreme case, blindness. In order to enhance the probability of treatment, it is meaningful to study the pathogenesis of pseudomonas aeruginosa keratitis further. The article reviews the pathogenicity of pseudomonas aeruginosa, and how the immunoreaction of host works in the pathogenesis of pseudomonas aeruginosa keratitis, thereby to provide theoretical basis of new methods for the treatment of pseudomonas aeruginosa keratitis.
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[基金项目]
云南省基础研究计划(昆医联合专项)\〖No.2018FE001(-265)\〗