[关键词]
[摘要]
角膜病变与糖尿病存在密切联系,严重者对视力构成威胁。目前,对糖尿病性角膜病变的治疗重点是预防感染和促进最佳的愈合环境。从细胞层次全面地理解病变发展过程对于识别和开发潜在的治疗药物至关重要。本文综述糖尿病性角膜上皮发生紊乱的现象以及其后续维持稳态的机制,并讨论其合理性。
[Key word]
[Abstract]
Keratopathy is closely related to diabetes, and severe cases pose a threat to vision. At present, the treatment of diabetic keratopathy focuses on preventing infection and promoting the optical healing environment. A comprehensive understanding of disease progression from the cellular level is essential for identifying and developing potential therapeutic agents. This article reviews the phenomenon of diabetic corneal epithelium disorder and its subsequent maintenance of homeostasis, and discusses its rationality.
[中图分类号]
[基金项目]
国家自然科学基金(No.81660158); 江西省青年科学基金(No.20151BAB215016,20161ACB21017); 江西省科技计划项目(No.20151BBG70223)