[关键词]
[摘要]
气候性滴状角膜变性(CDK)是一种以角膜前弹力层和基质层的油滴状沉积物及带状混浊为特征的获得性角膜退行性疾病，可严重影响患者的视力。目前研究认为CDK的发生、发展是多种因素协同作用的结果，但该病的发病特点及具体的发病机制尚不清楚。故本文通过对CDK的流行病学特点、角膜病变的组织形态、角膜沉积物的构成及CDK形成的微环境四个方面的研究进展进行综述，为眼科医生认识及探究CDK提供参考依据。
[Key word]
[Abstract]
Climatic droplet keratopathy(CDK), an acquired corneal degenerative disease, is characterized by oil droplet deposits and banded opacity in the pre-corneal elastic layer and stroma layer, which can severely affect the visual acuity of patients. Recently, many studies have indicated that various factors caused the occurrence and development of CDK. However, the pathogenesis and specific pathogenesis of the disease remain unclear. So this article aims to summarize four aspects of the CDK, including the epidemiological characteristics, the morphology of corneal lesions, the composition of corneal deposits and the ocular surface micro-environment, and then provide a reference for ophthalmologists to acknowledge and explore CDK deeply.
[中图分类号]
[基金项目]
新疆生产建设兵团中青年人才领军计划(No.2020CB030)
