[关键词]
[摘要]
甲状腺相关性眼病(thyroid-associated ophthalmopathy,TAO)是成人眼眶病中最常见的疾病,其眼部损害日益严重,对患者身心健康造成极大的伤害。TAO的发病机制十分复杂,目前还未完全阐明,经典理论为共抗原学说。鉴于现有治疗方案存在的弊端,研究与TAO相关的因素进而探求更好的治疗方法对TAO患者具有重要意义。近年来研究发现炎症反应与TAO关系密切,故本文就TAO相关炎性因素的研究做一综述。
[Key word]
[Abstract]
Thyroid-associated ophthalmopathy(TAO)is the most common orbital disease in adults. Its ocular damage is becoming more and more serious, which causes great harm to the physical and mental health of patients. The pathogenesis of TAO is very complex and has not yet been fully elucidated. The classical theory is the theory of co-antigens. In view of the drawbacks of existing treatment schemes, it is of great significance to study the factors related to TAO and explore better treatment methods for TAO patients. In recent years, the relationship between inflammatory response and TAO has been found, therefore this article reviews the research on TAO-related inflammatory factors.
[中图分类号]
[基金项目]
国家自然科学基金(No.81760179,81360151); 江西省自然科学基金项目一般项目(No.20171BAB205046); 江西省教育厅科技技术研究项目重点项目(No.GJJ160033); 江西省科技支撑计划项目(No.20141BBG70027); 江西省教育厅科学技术研究项目一般项目(No.GJJ13147); 江西省卫生计生委科技计划普通科技计划(No.20185118,20141031); 江西省基础健康适宜技术星火推广计划(No.20188007)