目的：探讨经25G微创玻璃体切除手术(PPV)治疗的眼内异物的临床特征及疗效，分析术后视力的影响因素。

方法：收集西南医科大学附属医院眼科2016-01-01/2019-01-01以眼内异物并行25G微创玻璃体切除手术治疗的患者105例105眼，对患者眼内异物的临床特征、PPV的疗效和最佳矫正视力(BCVA)等情况进行回顾性研究并统计分析术后视力的影响因素。

结果：患者105例中以中青年男性居多，多来自于乡镇。异物类型以金属常见，共计62眼(59.0%)，主要由Ⅰ区进入眼内(78眼， 74.3%)。术中异物取出率100%。术前BCVA≥0.1的患者17眼，BCVA<0.1者88眼； 术后BCVA≥0.1患者43眼，BCVA<0.1患者62眼，术后BCVA较术前 BCVA 有提高(P<0.05)。经多因素Logistic回归分析，术前较差的BCVA、视网膜脱离和眼内炎是术后视力较差的独立危险因素。

结论：25G微创玻璃体切除手术可以改善大多数眼内异物患者视力。术前较差的BCVA、合并视网膜脱离和眼内炎是术后视力较差的重要危险因素。

METHODS: Patients traumatized with retained IFB and treated with PPV were retrospectively collected from the Department of Ophthalmology, Affiliated Hospital of Southwest Medical University from 2016-1-1 to 2019-1-1. The clinical records including general condition, time and cause of injury, locations andsize of IFBs, comorbidities, and best corrected visual acuity(BCVA)were reviewed and statistical analyzed.

RESULTS: Among the 105 patients, most of them are middle-aged and young men, mostly from townships. The nature of IFB was mainly metals(62 cases, 59.0%). The entrance of IFB of 78 cases(74.3%)located at Zone I of the eye. There were 17 patients with BCVA≥0.1 before surgery, 88 patients with BCVA<0.1. And 43 patients gained BCVA≥0.1 after operation, and 62 patients with BCVA<0.1. Postoperative BCVA was significantly improved compared with preoperative BCVA(P<0.05). Through multivariate Logistic regression analysis, poor preoperative BCVA, retinal detachment, and endophthalmitis are risk factors for poor visual prognosis.

CONCLUSION: PPV for treatment of IFB can achieve a better outcome. The poor prognosis of visual acuity is related to retinal detachment, endophthalmitis, and the position and size of IFB.