目的：使用Pentacam检测健康、亚临床期和早期圆锥角膜患者角膜体积和前房容积。

方法：流行病学研究。共纳入63例屈光手术患者。根据Amsler-Krumeich标准，将患者分为正常、亚临床期和早期三组。收集了包括年龄和性别在内的人口统计信息，并获得了患者的完整病史。所有患者进行完整的视力检查。随后，使用Pentacam测量三组患者的角膜体积和前房容积。

结果：对照组角膜体积明显高于亚临床期组和早期组(P<0.05)，但两组间前房容积无显著性差异(P>0.05)。

结论：测量角膜体积有助于鉴别亚临床期圆锥角膜和早期圆锥角膜与正常眼。亚临床圆锥角膜患者、早期圆锥角膜患者和正常人的前房容积无显著差异。

METHODS: This epidemiologic study was performed on 63 patients who were candidates for refractive surgery. We classified our patients into three groups as normal, subclinical keratoconus, and early keratoconus according to the Amsler-Krumeich criteria. We collected demographic information, including age and sex, and obtained a full medical history of the patients. Complete visual examination was performed for all patients. Then, using Pentacam, corneal volume and anterior chamber volume were measured among three groups.

RESULTS: Corneal volume in the control group was significantly higher than the subclinical keratoconus and early keratoconus groups(P<0.05), but the anterior chamber volume was not significantly different between the groups(P>0.05).

CONCLUSION: Measuring the corneal volume can help to distinguish the eyes with subclinical keratoconus and early keratoconus from normal eyes. The chamber volume might not differ remarkably among people with subclinical keratoconus, early keratoconus, and those with normal eyes.