方法：回顾性分析2015-10/2019-03在我院行内镜下鼻腔泪囊吻合术治疗的280例316眼泪道疾病患者的病历资料，总结术后疗效并采用有序Logistic回归分析影响疗效的独立因素。

结果：术后所有患者临床治疗治愈率为52.2%，好转率为30.7%，无效率为17.1%。患者有无鼻炎(OR=95.58)、术后注入眼膏频率(OR=0.001)、既往是否有泪道置管术史(OR=0.0009)、既往是否有泪道激光术史(OR=94.73)、术中填塞材料可吸收与否(OR=0.002)是术后疗效的独立影响因素。

结论：鼻炎及泪道激光术史是降低内镜下鼻腔泪囊吻合术疗效的因素，术后定期注入眼膏、泪道置管术史及术中填塞可吸收材料均有利于提高手术疗效。

METHODS: Retrospectively analysis of the cases of 280 patients(316 eyes)with lacrimal duct diseases treated by endoscopic dacryocystorhinostomy in Hankou Eye Hospital of Wuhan Aier from Oct. 2015 to Mar. 2019, summarizd the efficacy and analyzed the independent factors of efficacy by using the ordered Logistic regression.

RESULTS: The total cure rate was 52.2%, the total improvement rate was 30.7%, and the total invalid rate was 17.1%. Rhinitis(OR=95.58), frequency of eye ointment injection after operation(OR=0.001), history of lacrimal duct catheterization(OR=0.0009), history of lacrimal laser(OR=94.73),packing material(OR=0.002)were the independent factor influencing the efficacy.

CONCLUSION: Rhinitis and history of lacrimal laser are the factors to reduce the curative effect of endoscopic dacryocystorhinostomy; regular injection of eye ointment after operation, history of lacrimal duct catheterization and filling of absorbable materials, which are beneficial to improve the curative effect of operation.