目的：观察自体穿透性角膜移植手术治疗角膜盲的临床效果。

方法：采用回顾性分析，选择2014-01/2018-03行自体穿透性角膜移植治疗的患者8例8眼(角膜盲)，随访1a，观察术中并发症、术后视力、术后角膜透明度和术后并发症等。

结果：术后1wk时8眼患者术后裸眼视力均>0.02，复明率100%； 术后1mo时5眼患者矫正视力超过0.3，3眼患者因术前白内障影响术后矫正，视力提高到0.08～0.2； 术后1a，8眼患者原角膜盲眼植片均透明，无感染复发或继发感染情况发生。

结论：自体角膜移植手术后角膜植片易于生长，无排斥反应，术后并发症较少，且治疗花费少，既可为单眼失明合并角膜盲的患者提供长期的有用视力，又可减轻其经济负担，为患者带来巨大利益。

METHODS: Totally 8 patients with corneal blindness were treated by autologous penetrating keratoplasty in our hospital from 2014-01 to 2018-03. Using retrospective analysis, the patients were followed up for one year. To observe the intraoperative complications and postoperative conditions such as visual acuity, corneal transparency, and other were observed.

RESULTS: The uncorrected visual acuity of all the 8 patients was greater than 0.02 1wk after operation, and the rate of restoration of visual acuity was 100%(8/8). The corrected visual acuity of 5 patients(5-8)was more than 0.3 1mo after operation. The corrected visual acuity of 3 patients(3-8)with severe cataract before operation was improved to 0.08-0.2. One year later, all the corneal grafts in the recipient eyes were transparency and no recurrence of infection or secondary infection occurred in all 8 patients.

CONCLUSION: Corneal graft is easy to grow and there are no exclusion reactions, fewer postoperative complications after autologous corneal transplantation. So, corneal implants can remain transparent for a long time, and the surgery cost is lower. Autologous corneal transplantation can not only provide long-term useful vision for patients with monocular blindness combined with corneal blindness, but also reduce their financial burden and bring great benefits to patients.