蓝光损伤视网膜的机制及防护

Mechanism and protection of retina injured by blue light

摘要:

蓝光是自然光线的重要组成部分，其波长主要介于400～500nm，是一种短波长光，它是高能可见光谱的一部分。蓝光损伤指的是由这一波长的辐射照射后引起的光化学作用，导致视网膜的损伤。可见光中蓝光对视网膜敏感性最高、穿透力最强，因而产生的光化学损伤作用最强，其中最主要损伤的是视网膜色素上皮细胞(RPE)和视网膜感光细胞。目前针对于蓝光的防护的研究已经逐步开展。本文依据现已证实的蓝光损伤视网膜的机制对其防护机制研究进展进行综述。

Abstract:

Blue light is an important part of natural light.The wavelength is mainly between 400nm and 500nm, which is a kind of short-wavelength light and a part of the high-energy visible spectrum. The damage of blue light refers to the photochemical action caused by radiation of this wavelength, resulting in damage to the retina. In the visible light, blue light has the highest sensitivity to the retina and the strongest penetrating power, so the photochemical damage is the strongest. The primary harm is to damage retinal pigment epithelium(RPE)and retinal photoreceptor cells. The research on the protection against the damage of blue light has been gradually carried out. In this paper, the research progress of its protective mechanism is discussed based on the currently study.