目的：观察中低度近视患者植入中央孔型有晶状体眼后房型人工晶状体(ICL V4c)术后的疗效及安全性。

方法：选取2016-01/2017-06在我院接受ICL V4c植入术的中低度近视患者20例40眼，术后1wk，1mo，1a进行随访，观察UCVA、BCVA、SE、眼压、角膜内皮细胞计数、拱高、术后不良反应及并发症。

结果：术后UCVA、BCVA均较术前提高(P<0.01)，术后1mo与术后1a UCVA无差异(P>0.05)，其余时间点UCVA两两比较均有差异(P<0.05)，术后各时间点BCVA两两比较均无差异(P>0.05)。术后SE均较术前降低(P<0.01)，术后1wk平均SE接近0D。术后1a手术安全指数为1.05±0.14，手术有效性为1.07±0.14。术后各时间点与术前眼压均无差异(P>0.05)。术后1a角膜内皮细胞密度与术前无差异(P>0.05)。所有研究对象均未见白内障、青光眼、角膜内皮失代偿等。术后满意度为100%。

结论：ICL V4c植入术是治疗中低度近视安全而有效的方法，术后1mo后视力稳定。

METHODS: Twenty low to moderate myopia patients(forty eyes)who underwent the ICL V4c implantation in our hospital from January 2016 to June 2017 were observed 1wk, 1mo and 1a after operation respectively. Uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), equivalent spherical mirrors(SE), intraocular pressure, corneal endothelial cell count, ICL-vault, adverse reaction and complication were investigated.

RESULTS: Postoperative UCVA and BCVA were significantly higher than that in preoperative group(P<0.01). Significant difference was found in UCVA between postoperative groups except between 1mo and 1a. No significant difference were found in BCVA among postoperative groups(P<0.05). Postoperative SE at all time points were lower than that in preoperative group(P<0.01). Average SE after 1wk after operation were close to 0 diopter. The safety index in 1a postoperative were 1.05±0.14 and the effective index was 1.07±0.14. No significant difference was found in intraocular pressure and endothelial cell density after surgery comparing to that in preoperative group(P>0.05). None of subjects developed cataract, glaucoma and decompensation of corneal endothelium. The degree of postoperative satisfaction was 100%.

CONCLUSION: ICL V4c implantation is a safe and effective method for the correction of low to moderate myopia. The visual acuity stabilized 1mo after operation.