[关键词]
[摘要]
角膜新生血管(corneal neovascularization，CNV)的产生是角膜盲的常见原因，但到目前为止，还没有十分有效的治疗方法。CNV面积这一参数在衡量药物或治疗方案效果好坏时具有重要参考价值。目前有多种方法可对CNV进行显影，包括墨汁灌注、免疫荧光染色等，近年来的光学相干断层成像技术等也是极有潜力的新方法。本文综述了显影CNV的相关方法，希望能对CNV的研究提供参考。
[Key word]
[Abstract]
Corneal neovascularization(CNV)is a common cause of corneal diseases, but there is still no effective drug or treatment. At present, the common methods cannot inhibit the growth of CNV completely, cannot last for a long the therapeutic effect time, and there are also serious side effects, so the specific treatment of CNV inhibition is still being explored. The pathogenesis and treatment of CNV are the current research hotspots. CNV area is an important indicator to evaluate the efficacy of drugs and treatment regimens. There are multiple methods to develop CNV, including ink perfusion, immunofluorescence staining and so on, in recent years, optical coherence tomography(OCT)technology is also a potential new method. This article reviews the developing methods of CNV, hopes to provide a reference for the study of CNV.
[中图分类号]
[基金项目]
吉林省科技厅自然科学基金(No.20180101146JC); 吉林省科技发展计划项目(No.20160520153JH)
