系统性疾病患者角膜神经丛和郎格汉斯细胞的共聚焦显微镜观察

Confocal microscopy observation of corneal nerve plexus and Langerhans cells in patients with systemic diseases

摘要:

角膜共聚焦显微镜(corneal confocal microscope，CCM)是一种非侵入性、用于研究活体角膜的方法，其越来越多地被用以评估角膜神经丛和郎格汉斯细胞病变。本文对应用CCM研究糖尿病、干燥综合征、多发性硬化、甲状腺相关性眼病、纤维肌痛、慢性偏头痛、帕金森病等系统性疾病中的角膜神经丛和郎格汉斯细胞病变的新进展进行综述。

Abstract:

Corneal confocal microscope(CCM)is a non-invasive instrument for the study of living cornea and is increasingly being used to evaluate corneal nerve plexus and Langerhans cell lesions. This paper reviews the recent advances in corneal nerve plexus and Langerhans cell lesions from the perspective of the use of CCM in the study of systemic diseases such as diabetes mellitus, Sjogren's syndrome, multiple sclerosis, thyroid-associated ophthalmopathy, fibromyalgia, chronic migraine and Parkinson's disease.