目的：对比眼前节分析仪(Wavelight)、IOL Master、光学生物测量仪(LS900)及AS-OCT与量规测量角膜直径的差异。

方法：选取2015-06/2018-01拟于本院行ICL V4c矫正屈光不正患者89例177眼，ICL植入手术前分别用Wavelight、IOL Master、LS900测量角膜横径(WTW)，用AS-OCT测量房角之间的距离(ATA)，也就是从内部测量角膜横径，然后显然验光及散瞳验光，第2d用量规测量角膜直径并做比较，以量规测量值输入厂家公式计算ICL直径，并做植入。用OCT检查术后3mo拱高等参数。

结果：Wavelight、IOL Master、LS900测量WTW平均值分别为12.45±0.73、11.96±0.39、11.92±0.36mm，用AS-OCT测量ATA平均为11.80±0.44mm。量规测量WTW为11.49±0.30mm，量规测量值均比四种仪器测量值小(P<0.01)。LS900测量值比IOL Master小(P=0.098)，可相互替代，其他仪器之间均有差异(P<0.01)。以量规测量值为基础计算的ICL V4c直径平均为12.77±0.37mm，植入术后3mo用OCT检查拱高为537.41±181.22μm。

结论：四种仪器测量角膜直径值可做参考； 以量规为基础计算的ICL术后拱高是理想的； 在设计ICL大小时，量规是理想的测量角膜直径的工具，不可替代。

METHODS: Totally 89 patients(177 eyes)with myopia who want to accept ICL were examined before operation with more than five kinds of instruments respectively, white to white(WTW)were examined with Wavelight, IOL-master, LS900 and gauge, angle to angle(ATA)with AS-OCT. Then the size of ICL was calculated based on the value of gauge. The vault of ICL was examined with OCT 3mo after operation.

RESULTS: WTW was(12.45±0.73, 11.96±0.39, 11.92±0.36, 11.49±0.30)mm measured by Wavelight, IOL-Master, LS900 and gauge respectively, ATA was(11.80±0.44)mm with AS-OCT. The value of gauge was the smallest one among them(all P<0.01). Among four instruments, there was no statistical difference between LS900 and AS-OCT(P=0.098), they can instead of each other; there were differences among other instruments(P<0.01). The size of ICL based on gauge was(12.77±0.37)mm. The vault of ICL is(537.41±181.22)μm 3mo after implantation obtained by OCT.

CONCLUSION: Gauge is ideal tool for measuring corneal diameter, it cannot be instead. Wavelight, IOL Master, LS900 and AS-OCT can be taken as reference.