目的：探讨中央孔型ICL V4c植入术矫正中高度近视的稳定性及对高阶像差的影响。

方法：观察采用ICL V4c人工晶状体植入术(研究组17例34眼)和全飞秒小切口基质透镜取出术(SMILE)(对照组18例34眼)治疗的高度近视患者术前、术后1d，1wk，1、3mo UCVA、BCVA、球镜(SE)、柱镜(CE)、IOP、角膜内皮细胞计数、总高阶像差(RMS)、球差、垂直彗差、水平彗差、彗差的差异。

结果：术后1、3mo研究组SE、CE高于对照组(P<0.05)，术后1wk，1、3mo RMS、彗差低于对照组(P<0.05)，术后3mo球差、水平彗差低于对照组(P<0.05)。

结论：ICL V4c植入术矫正中高度近视眼具有良好稳定性，对术眼高阶像差影响小。

METHODS: The differences of uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), spherical equivalent(SE), cylinder equivalent(CE), intraocular pressure(IOP), corneal endothelial cell count, total high order aberration(RMS), spherical aberration, vertical coma, horizontal coma, coma were compared among high myopia patients who treated with ICL V4c intraocular lens implantation(research group: 17 cases, 34 eyes)and femtosecond small incision matrix lens extraction(SMILE)(control group: 18 cases, 34 eyes)before operation(T0), 1d after operation(T1), 1wk after operation(T2), 1mo after operation(T3), 3mo after operation(T4)respectively.

RESULTS: SE and CE in research group were higher than those in control group at T3-T4(P<0.05), RMS of higher order aberration and coma at T2-T4 were lower than those in control group(P<0.05), spherical aberration and horizontal coma at T4 were lower than those in control group(P<0.05).

CONCLUSION: ICL V4c implantation is stable in the correction of moderate and high myopia, and has little effect on high order aberration.