目的：探讨飞秒激光制瓣LASIK术对屈光参差患者调节功能的影响。

方法：采用系列病例观察试验设计。收集行飞秒激光制瓣LASIK术的近视性屈光参差患者35例70眼，分别于术前和术后1、3mo进行随访观察，检测裸眼远视力、远用等效球镜度、双眼屈光度差值、单眼调节幅度、正负相对调节、调节滞后量。

结果：术后1、3mo的裸眼远视力明显提高，远用等效球镜度、双眼屈光度差值较术前明显降低； 术后3mo的单眼调节幅度和正相对调节较术前戴镜明显提高(P<0.05)； 术前戴镜、术后1mo裸眼、术后3mo裸眼的负相对调节、调节滞后量差异无统计学意义(P>0.05)。

结论：飞秒激光制瓣LASIK术治疗近视性屈光参差是一种安全有效的术式，手术未对患者的调节功能产生不良影响，可能有助于恢复双眼协调一致的调节功能。

METHODS: A respective serial case observational study was designed. Thirty-five patients(70 eyes)with myopic anisometropia treated by FEMTO LASIK were included in the study. Their uncorrected distance visual acuity, distance spherical equivalent, the difference of binocular diopter and accommodative functions including amplitude of accommodation, negative relative accommodation, positive relative accommodation and lag of accommodation were measured three times(before surgery, 1mo and 3mo after surgery).

RESULTS: At 1mo and 3mo after surgery, uncorrected distance visual acuity was improved significantly, distance spherical equivalent and the difference of binocular diopter were significantly decreased. Amplitude of accommodation and positive relative accommodation were improved at 3mo after surgery. The differences were statistically significant. There was no statistically significant difference of negative relative accommodation and lag of accommodation between these three times.

CONCLUSION: FEMTO LASIK for the correction of myopic anisometropia is an effective and safe procedure. The surgery may have no adverse influence on patients' accommodative function. It would be helpful for recovery of the binocular coordinate accommodative function.