三七粉治疗玻璃体切除术后再出血的疗效观察

Clinical efficacy of pseudo-ginseng powder for post-vitrectomy vitreous hemorrhage in diabetic patients

摘要:

目的：观察三七粉对于玻璃体切除术后再出血患者的疗效，为该类患者的药物治疗提供新的方向。

方法：纳入2010-01/2017-12在我院眼科就诊的玻璃体切除术后再出血的增殖性糖尿病视网膜病变患者共32例32眼，予三七粉口服，1.5g/次，2次/d，7d为一疗程，连续服用3个疗程后进行观察评估。统计治疗前后患者视力情况、光学相干断层扫描成像质量、玻璃体出血等级，从而判断其疗效。

结果：经过3个疗程的治疗后，所有患者均未出现服药后不良反应，总体视力改善率为88%，最佳矫正视力(LogMAR)治疗前为1.93±0.46，治疗后为1.42±0.5。其中治疗前小数视力≥0.02、指数～<0.02、光感的患者治疗后视力改善率为100%，治疗前手动的患者治疗后视力改善率为60%。所有患者光学相干断层扫描成像质量总体改善率为94%，玻璃体出血等级总体改善率为94%。

结论：三七粉能有效治疗玻璃体切除术后再出血患者，其能促进玻璃体腔积血吸收，使患者视力尽快提高并且降低二次手术概率。

Abstract:

AIM: To evaluate the efficacy of pseudo-ginseng power for post-vitrectomy vitreous hemorrhage in diabetic patients and provide new insight into the treatment options.

METHODS: Totally 32 eyes of 32 patients with post-vitrectomy hemorrhaged secondary to proliferative diabetic retinopathy were included. Patients were prescribed with pseudo-ginseng powered, 1.5g, twice a day, for 3 consecutive sections(21d). The visual acuity, optical coherence topography image quality and degree of vitreous hemorrhage was assessed before and after the treatment were analyzed to evaluate the efficacy of pseudo-ginseng powder.

RESULTS: No adverse reaction was seen in all subjects after 21d of treatment. And 88% of the patients had improved visual acuity. The mean best corrected visual acuity(LogMAR)was 1.93±0.46 and 1.42±0.5, before and after treatment, respectively. For the patients with visual acuity no worse than 0.02, finger counting to less than 0.02 and light perception, the improvement rate was 100%. For patients with visual acuity from hand motion, the improvement rate was 60%. The improvement rate for optical coherence tomography image quality was 94%, and 94% for degree of vitreous hemorrhage.

CONCLUSION: Pseudo-ginseng power is effective in patients with postvitrectomy hemorrhaged secondary to proliferative diabetic retinopathy. It accelerated the elimination of vitreous hemorrhage and improved the visual acuity as well as decreased the likelihood of re-cooperation.