方法：选取2016-01/2017-01在我院收治的青少年儿童近视患者150例282眼，根据患者及其家属意愿分为角膜塑形镜组和框架镜组。框架镜组进行常规配镜治疗，角膜塑形镜组患者给予角膜塑形镜进行矫正，在治疗前和治疗1a后对所有患者的视力情况进行检测统计，记录矫正前后两组患者的角膜曲率、角膜中央厚度和屈光度并进行比较，同时统计两组患者治疗期间并发症的发生率。

结果：角膜塑形镜组患者治疗后的裸眼视力显著优于框架镜组患者治疗后的裸眼视力，差异具有统计学意义(P<0.05)。治疗后的角膜曲率角膜塑形镜组显著低于框架镜组，差异具有统计学意义(P<0.05)。两组患者治疗前、治疗后角膜中央厚度比较，差异不具有统计学意义(P>0.05)。两组患者治疗前屈光度比较，差异无统计学意义(P>0.05)； 治疗后的屈光度角膜塑形镜组明显低于框架镜组，差异具有统计学意义(P<0.05)。角膜塑形镜组患者的并发症发生率为14.3%，显著高于框架镜组的4.9%，差异具有统计学意义(P<0.05)。

结论：角膜塑形镜治疗近视患者效果显著，但患者并发症发生情况较多，临床应用过程中应针对可能会引发并发症的因素进行针对性地防范，使治疗过程更加安全。

METHODS: Totally 150 cases of myopia children admitted to our hospital from January 2016 to January 2017 were selected and divided into the orthokeratology lens group and the spectacles group according to the wishes of the patients and their families. Visual acuity of all patients was examined before and 1a after treatment. corneal curvature, corneal thickness and diopter were recorded and the complications during treatment was observed as well.

RESULTS: The uncorrected visual acuity of orthokeratology lens group was significantly better than that of spectacles group(P<0.05). The corneal curvature of orthokeratology lens group was significantly lower than that of spectacles group(P<0.05). There was no significant difference in central corneal thickness of the two groups before and after treatment(P>0.05). There was no significant difference in diopter between the two groups before treatment(P>0.05); the diopter of orthokeratology lens group was significantly lower than that of spectacles group(P<0.05). The incidence of complications in orthokeratology lens group was 14.3%, which was significantly higher than that in spectacles group 4.9%(P<0.05).

CONCLUSION: The treatment of myopia with orthokeratology lens has a significant effect, but there are many complications in the patients. Therefore, in the clinical application process, specific precautions should be taken against the factors that may cause complications, so as to make the treatment process safer.