息肉样脉络膜血管病变的临床特征与手术治疗进展

Clinical features and progress of surgical therapy for polypoidal choroidal vasculopathy

摘要:

息肉样脉络膜血管病变(polypoidal choroidal vasculopathy，PCV)是一组以脉络膜异常分支血管网及末端息肉样血管扩张病灶为特征的眼底疾病，临床治疗较为棘手。大面积视网膜黄斑下出血(submacular hemorrhage，SMH)甚至玻璃体腔出血是PCV的严重并发症，往往需要手术干预。其手术治疗包括气体填充和/或组织型纤溶酶原激活物(tPA)注射、玻璃体切割联合视网膜切开或外路引流等。本文就目前国内外关于PCV的临床特征、并发症及手术治疗新进展等内容进行综述。

Abstract:

Polypoidal choroidal vasculopathy(PCV)is a fundus disease characterized by choroidal anomalous branch vascular network and terminal polypoidal dilatation. Submacular hemorrhages(SMH)and vitreous hemorrhage are devastating complications of PCV. Various techniques are available for the management of SMH, including pneumatic displacement with or without tissue plasminogen activator(t-PA), submacular surgery with vitrectomy and retinotomy/external drainge for clot extraction. This article reviews PCV clinical features, complications and especially new advances in surgery.