[关键词]
[摘要]
视网膜色素变性(retinitis pigmentosa,RP)是一组遗传性视网膜疾病,其特征是渐进性感光细胞和视网膜色素上皮(RPE)细胞功能障碍,是世界范围内常见的致盲性眼病,且缺乏有效的治疗方法。目前RP的治疗方法包括干细胞治疗、基因治疗、神经保护治疗、营养疗法、高压氧疗法、视网膜移植和中医治疗。本文综述了近年来国内外有关RP治疗的研究进展。
[Key word]
[Abstract]
Retinitis Pigmentosa(RP)is a group of inherited retinal diseases characterized by progressive photoreceptor cells loss and pigment epithelial cell dysfunction. It is one of the most common disease worldwide which leads to blindness, and there were no effective treatments for RP in the past decades. Recently, lots of methods were considered effective to treat with RP, including stem cell therapy, gene therapy, neuroprotective therapy, nutritional therapy, hyperbaric oxygen therapy, retinal transplantation and traditional Chinese medicine. In this review, we conducted a comprehensive analysis and assessment on the findings of the progress of RP treatment at domestic and overseas.
[中图分类号]
[基金项目]
湖南省教育厅创新平台开放基金项目(No.16K065); 湖南中医药大学中医诊断学国家重点学科开放基金优先资助项目(No.2015ZYZD02); 中医药防治五官科疾病湖南省重点实验室建设项目(No.2017TP1018); 长沙市科技计划项目(No.kc1704005); 国家中医药管理局中医眼科学重点学科建设项目; 湖南省中医五官科学重点学科建设项目