[关键词]
[摘要]
视网膜母细胞瘤(retinoblastoma,RB)是婴幼儿最常见的眼内恶性肿瘤,其发病与基因突变相关。为提高患儿生存率,降低眼球摘除率,治疗方法不断更新发展。目前主要治疗方法有化学治疗、放射治疗、手术治疗、物理治疗、光化学治疗、基因治疗等。本文就视网膜母细胞瘤的治疗进展进行综述。
[Key word]
[Abstract]
Retinoblastoma(RB)is the most common intraocular malignant tumor in infants, the pathogenesis of which, is related to gene mutations. In order to improve the survival rate and eye-protection rate of RB patients, the therapeutic approaches have been constantly updated and developed, mainly including chemotherapy, radiation therapy, surgical treatment, physiotherapy, photochemotherapy, gene therapy at present. In this article, we mainly reviewed the progress of RB treatment.
[中图分类号]
[基金项目]
国家自然科学基金(No.81501487,81170858)