[关键词]
[摘要]
目的：评估白内障超声乳化摘除手术对睑板腺功能的影响，并探讨其对眼表的潜在影响。
方法：采取前瞻性自身对照研究。选取患有年龄相关性白内障的睑板腺功能障碍患者56例56眼，分别于术前1d，术后2wk，1、3mo进行眼表疾病指数(ocular surface disease index，OSDI)问卷评分、睑板腺积分、睑缘形态评分、基础泪液分泌试验(SⅠt)、泪膜破裂时间(BUT)的评估。
结果：手术前后，SⅠt试验差异无统计学意义(P>0.05)； 而OSDI评分、睑板腺积分、睑缘形态评分、BUT均较术前有明显变化，差异均有统计学意义(P<0.05)。术后2wk，1、3mo OSDI评分、睑板腺积分、睑缘形态评分均较术前1d明显升高，差异均有统计学意义(P<0.05)； 术后2wk，1、3mo BUT均较术前1d明显缩短，差异均有统计学意义(P<0.05)。
结论：白内障手术可能加重睑板腺功能障碍。
[Key word]
[Abstract]
AIM: To evaluate meibomian gland dysfunction(MGD)after phacoemulsification surgery, and to
discuss the potential impact of ocular surface.
METHODS: A perspective, self-controlled clinical trial was conducted. Fifty-six eyes of 56 patients with MGD underwent phacoemulsification and were evaluated the ocular surface disease index(OSDI), meibography score, lid margin abnormalities, Schirmer test, tear film break-up time(BUT)at preoperatively and postoperatively 2wk, 1 and 3mo.
RESULTS: Schirmer test did not change significantly postoperatively(P>0.05). The OSDI scores, meibography score, lid margin abnormalities increased at 2wk, 1 and 3mo postoperatively compared to before operation(all P<0.05); BUT decreased(P<0.05).
CONCLUSION: Meibomian gland function may be aggravated after phacoemulsification surgery.
[中图分类号]
[基金项目]
新疆维吾尔自治区自然科学基金(No.2016D01C129)
