[关键词]
[摘要]
阿尔茨海默病(AD)是一种神经系统退行性疾病，以痴呆为主要表现，常伴有记忆力进行性减退及个人自理能力的丧失，严重影响生活质量。AD目前尚无治愈的方法，用药仅能控制疾病的进展。早期诊断并控制疾病进展，对于提高患者的生活质量，减轻家庭及社会负担意义重大。眼科检查被视为可以直接“看到”大脑病变的窗户，眼部的一些改变能够最直接地反映大脑的变化。本文梳理了眼科关于AD的相关检查，包括光学相干断层扫描仪(OCT)、视野、对比敏感度和眼球运动等，以期为AD的早期诊断提供新的思路。
[Key word]
[Abstract]
Alzheimer's disease is a progressive neurodegenerative disorder causing irreversible deterioration in memory and loss of self-care ability, which is seriously affecting the quality of life. There is no cure for Alzheimer's disease. Medication only can control the progression of the disease. Early diagnosis and control of disease progress is of great significance in improving the quality of life of the patients and reducing the burden of family and society. Ophthalmic examination is seen as a window which can “see” brain directly, and some changes in the eye can reflect the changes of the brain most directly. This paper reviews the ophthalmic examination of Alzheimer's disease, including optical coherence tomography(OCT), visual field, contrast sensitivity and eye movements, et al. We hope to provide a new idea for the early diagnosis of Alzheimer's disease.
[中图分类号]
[基金项目]
重庆市科学技术委员会资助项目(No.cstc2015jcsf10012-2)
