目的：探讨视知觉学习纠正儿童屈光参差性弱视的长期疗效。

方法：回顾性分析本院2014-08/2016-08收治的200例200眼屈光参差性弱视患儿的临床资料，根据治疗方法分为两组，对照组(82例82眼)采用传统综合疗法进行治疗，观察组(118例118眼)采用视知觉学习进行治疗。共治疗1a，对比两组患儿治疗前后的矫正视力、对比敏感度和立体视锐度。

结果：治疗1a，观察组有效率高于对照组(90.7% vs 75.6%，P<0.05)； 随访1a，观察组随访期内有92.5%的患者保持稳定，而对照组为80.6%，观察组高于对照组，组间差异有统计学意义(P<0.05)。两组患者治疗前对比敏感度比较，差异无统计学意义(P>0.05)； 治疗6mo和12mo，两组患者的对比敏感度均有明显提高，差异有统计学意义(P<0.05)； 且治疗12mo时，观察组的对比敏感度高于对照组，组间差异有统计学意义(P<0.05)。治疗前，两组患者的立体视锐度比较，差异无统计学意义(P>0.05)； 治疗后，观察组立体视锐度优于对照组，组间差异有统计学意义(P<0.05)。

结论：视知觉学习纠正儿童屈光参差性弱视的长期疗效优于传统综合疗法。

METHODS: The clinical data of 200 children(200 eyes)with anisometropic amblyopia were retrospectively analyzed, which were divided into 2 groups according to therapeutic methods, and 82 children treated with traditional integrative therapy were distributed to the control group, while 118 children treated with visual perceptual learning were distributed to the observation group. After 1 year's treatment, the corrected vision, contrast sensitivity and stereo sharpness of patients were compared between groups.

RESULTS: After 1 year's treatment, the effective rate of the observation group was higher than the controls(90.7% vs 75.6%, P<0.05), and after 1 year's follow up, there was 92.5% patients maintained stabilization in the observation group, while that in the control group was 80.6%, and the observation group was higher than the controls too, the difference between groups had statistical significance(P<0.05). Before treatment, there was no significant difference in contrast sensitivity between groups(P>0.05). After 6 and 12 months' treatment, the contrast sensitivity of both groups increased(P<0.05), and the observation group was higher than the controls after 12 months' treatment, the difference between groups had statistical significance(P<0.05). Before treatment, there was no significant difference in stereopsis acuity between groups(P>0.05). After treatment, the stereopsis acuity of the observation group was better than the controls, and the difference between groups had statistical significance(P<0.05).

CONCLUSION: The long-term curative effect of visual perception learning to correct children's refractive aberration is better than traditional comprehensive therapy.