目的：观察Nd：YAG激光消融术治疗玻璃体混浊的疗效。

方法：回顾性分析2016-10/2017-01我科收治并确诊为玻璃体混浊并采用Nd：YAG激光治疗的患者78例84眼的临床资料，采用χ²检验、Mann-Whitney检验、Kruskal-Wallis检验和Spearman检验等比较不同病因和玻璃体分级间的治疗效果。

结果：治疗2wk后，所有患眼(84眼)中显效66眼(79%)，有效16眼(19%)，无效2眼(2%)，激光治疗的总有效率为98%； 不同病因引起的玻璃体混浊，其治疗效果和治疗次数差异没有统计学意义(H=3.842，P=0.146； χ²=0.070，P=0.966)； 玻璃体混浊Ⅰ级、Ⅱ级的治疗有效率均为100%，Ⅲ级为92%，Ⅳ级为83%，玻璃体混浊分级与疗效呈负相关(r_s=-0.027，P=0.013)。Ⅰ级患眼需要治疗1次的有38眼(90%)，Ⅱ级的有21眼(88%)，Ⅲ级的有9眼(75%)，Ⅳ级的有2眼(33%)，不同分级的患眼治疗次数差异具有统计学意义(U=2.580，P=0.010)。

结论：Nd：YAG激光玻璃体消融术是治疗玻璃体混浊的一种操作简单、方便，能快速改善飞蚊症状的治疗方法。

METHODS: From October 2016 to January 2017, 78 cases(84 eyes)with vitreous floaters treated with Nd:YAG laser ablation were involved. Chi-square test, Mann-Whitney Test, Kruskal-Wallis test and Spearman test were used to compare the therapeutic effect with different etiologies and grades.

RESULTS: After two-week treatment, there were 66 eyes(79%)with a significant resolution, 16 eyes(19%)with an improvement and 2 eyes(2%)invalid. The total effective rate was 98%. There was no significant difference between the therapeutic effect and times in different etiologies(H=3.842,P=0.146; χ²=0.070, P=0.966); the effective rate were 100% in grade Ⅰ and Ⅱ, 92% in grade Ⅲ, 83% in grade Ⅳ, and the grade had a negative correlation with the therapeutic effect(r_s=-0.027, P=0.013). There were 38 eyes(90%)in grade Ⅰ, 21 eyes(88%)in grade Ⅱ, 9 eyes(75%)in grade Ⅲ, and 2 eyes(33%)in grade Ⅳ needed once treatment. There was significant difference between different grades and treatment times(U=2.580, P=0.010).

CONCLUSION: Nd:YAG laser ablation is a simple and convenient operation for vitreous floaters, and could improve the symptom of vitreous floater rapidly.