目的：对微小切口基质透镜切除术(SMILE术)矫正高度散光与低度散光前后表面曲率、前房深度变化进行观察比较。

方法：选取2013-04/2017-01在我院行SMILE术治疗的复合性近视散光的患者共63例88眼，等效球镜为-4.00～-9.00D，根据散光情况分为两组，其中A组柱镜度数为-2.00～-4.00D，B组柱镜度数为-0.25～-1.00D。常规围手术期检查。所有病例按照SMILE术式常规操作流程完成手术，术后常规抗炎、抗菌药物治疗。随访视力、眼压、屈光度及角膜地形图(Pentacam)至术后3mo。观察对比A、B组前后表面曲率、前房深度变化。A、B组数据之间的比较采用独立样本t检验，A、B组各时间段之间的数据进行重复测量数据的方差分析后再进行两两比较。

结果：患者88例手术均顺利完成，边缘Ⅰ级愈合。A、B两组在术前、术后1wk，1、3mo时，后表面曲率及前房深度差异无统计学意义(P>0.05)。A、B两组前表面曲率术后1wk时较术前均有明显变化(P<0.05)，术后1wk，1、3mo时两两相比差异无统计学意义(P>0.05)。

结论：无论是SMILE术矫正高度散光还是低度散光，角膜后表面的曲率及前房深度均无明显变化，前表面曲率在术后1wk稳定。

METHODS: Sixty-three cases(88 eyes)undergone SMILE in our hospital were included. The patients were divided into two groups based on astigmatism degree: the Group A: -2.00D to -4.00D astigmatism, the Group B: -0.25D to -1.00D astigmatism. Patients were examined at 1wk, 1 and 3mo after operations. Visual acuity, intraocular pressure, refraction, corneal curvature and anterior chamber depth were recorded. The change of anterior and posterior corneal curvature and anterior chamber depth was compared. Spearman correlation analysis and independent t test were used for statistical analysis.

RESULTS: Surgery was done well in all patients without complications. No statistically significant difference was found between the two groups in posterior corneal curvature and anterior chamber depth preoperatively, postoperatively 7d,1 and 3mo(P>0.05). One week postoperatively, the anterior corneal curvature was statistically significant from that of preoperative in both groups(P<0.05), while there were no significant differences at 1 and 3mo after operation(P>0.05).

CONCLUSION: No significant change of anterior and posterior corneal curvature and anterior chamber depth was found after SMILE for correcting low and high myopic astigmatism. One week after SMILE the anterior corneal curvature become stable.