目的：评估急性共同性内斜视(acute-onset comitant esotropia，ACE)双眼复视患者行压贴三棱镜矫正前后视觉相关生活质量及双眼视功能。

方法：回顾性病例研究。收集2014-03/2017-03于湖州市中心医院因双眼复视就诊并诊断为ACE的患者16例，采用25项美国国家眼科研究所视觉功能问卷调查(25-item National Eye Institute Visual Function Questionnaire，NEI-VFQ-25)中文版评估三棱镜矫正前后患者的视觉相关生活质量。同时记录ACE双眼复视患者三棱镜矫正前及矫正后1mo的Worth 4点灯检查、立体视检查等临床资料。数据采用配对样本t检验、卡方检验及Fisher确切概率法进行分析。

结果：(1)患者行压贴三棱镜矫正后1mo的视觉相关生活质量，包括一般健康状态、总体视觉情况、精神健康状态、社会角色限制、社交功能、近距离工作、远距离工作、独立性和驾驶等方面评分较矫正前均明显提高，差异均有统计学意义(P<0.05)，但在周边视野、色彩视觉和眼痛方面差异均无统计学意义(P>0.05)。(2)患者行压贴三棱镜矫正前后的远距离融合功能和近立体视功能差异均有统计学意义(P<0.05)。

结论：压贴三棱镜能够改善ACE双眼复视患者的视觉相关生活质量及双眼视功能。

METHODS: Retrospective case-series study. Totally 16 acute-onset comitant esotropia patients with diplopia who received treatment in the Huzhou Central Hospital were included in this study from March 2014 to March 2017. Vision-related quality of life before press-on prism correction and 1mo after press-on prism correction were performed with the Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire(CHI-NEI-VFQ-25). In each time of follow-up, we made a minute examination, includes worth four dot test and stereo tests. Data was statistically analyzed with paired sample t test, Chi-square test and Fisher's exact test.

RESULTS: Except the degree of eye pain, color vision and perimetry, the indicators from CHI-NEI-VFQ-25 table including general health status, overall vision, mental health, social role difficulties, social functional, near activities, distant activities, independency and driving of acute-onset comitant esotropia patients with diplopia were obviously significant improved 1mo after press-on prism correction(P<0.05). One month after press-on prism correction, the fusion function and stereo acuity were significant enhanced(P<0.05).

CONCLUSION: Press-on prism correction may be helpful for binocular vision recovery in acute-onset comitant esotropia patients with diplopia, so as improve the vision-related quality of life.