目的：研究睑板腺管按摩联合药物治疗睑板腺功能障碍(meibomian gland dysfunction，MGD)的效果。

方法：选取2014-12/2016-12在我院进行治疗的MGD患者100例189眼，随机将患者分为对照组和观察组。对照组患者进行常规药物治疗，观察组患者在常规药物治疗的基础上给予睑板腺按摩。观察并比较两组患者临床疗效，以及治疗前和治疗后1wk，1、3mo患者的主观症状、泪膜破裂时间、泪液分泌试验、眼表疾病指数、角膜染色评分情况。

结果：观察组患者临床总有效率为93.6%，显著高于对照组患者(P<0.05)。两组患者治疗后主观症状、眼表疾病指数、角膜染色评分较治疗前下降，泪膜破裂时间、泪液分泌试验值较治疗前上升(P<0.05)。观察组患者主观症状、眼表疾病指数、角膜染色评分下降幅度及泪膜破裂时间、泪液分泌试验值上升幅度大于对照组患者(P<0.05)。

结论：睑板腺管按摩联合药物治疗可提高MGD的临床疗效。

METHODS: Totally 100 patients(189 eyes)with MGD were selected in our hospital from December 2014 to December 2016. The patients were randomly divided into control group and observation group. Patients in the control group were treated with routine drugs, while the patients in the observation group were treated with routine massage. We observed and compared the clinical efficacy of two groups of patients before treatment, 1wk, 1 and 3mo after treatment for the subjective symptoms, tear film break-up time, tear secretion test, ocular surface disease index, corneal staining score of the patients in the 3 groups.

RESULTS: The total effective rate of the observation group was 93.6%, which was significantly higher than that of the control group(P<0.05). Two groups of patients after treatment of subjective symptoms, ocular surface disease index, corneal staining score decreased, tear break-up time, Schirmer test was increased compared with before treatment(P<0.05). The decrease of subjective symptoms, ocular surface disease index, corneal staining score, the increase of tear film break-up time, tear secretion test in the observation group were higher than those in the control group(P<0.05).

CONCLUSION: Massage combined with medication can improve the clinical efficacy of MGD.