目的：观察高度近视白内障患者术后泪膜及角膜内皮细胞密度情况。

方法：选取2016-01/12我院收治的高度近视白内障患者38例38眼作为研究组，其中男24例24眼，女14例14眼，年龄60～72(平均65.2±2.37)岁。无高度近视的年龄相关性白内障患者38例38眼作为对照组，其中男22例22眼，女16例16眼，年龄61～70(平均64.4±2.43)岁。比较两组患者术前，术后3、7、14d，1mo泪膜及角膜内皮细胞密度情况。

结果：两组术前SⅠt、BUT、FL、主观感觉评分、角膜内皮细胞密度比较，差异均无统计学意义(P>0.05)。两组术后3、7、14d、1mo BUT、FL、角膜内皮细胞密度、主观感觉评分比较，差异均有统计学意义(P<0.01)。两组术后3、7、14d SⅠt比较差异均有统计学意义(P<0.01)，术后1mo比较差异无统计学意义(P>0.05)。两组患者术后3、7、14d，1mo FL、主观感觉评分、角膜内皮细胞密度较同组术前比较，差异均有统计学意义(P<0.01)。两组术后3、7、14d SⅠt与同组术前比较差异均有统计学意义(P<0.01)，术后1mo与同组术前比较差异均无统计学意义(P>0.05)。高度近视年龄相关性白内障患者术后3、7、14d，1mo BUT比同组术前降低，差异均有统计学意义(P<0.01)， 无高度近视年龄相关性白内障患者术后3、7、14d比同组术前降低，差异均有统计学意义(P<0.01)，术后1mo与术前比较差异无统计学意义(P>0.05)。

结论：超声乳化白内障手术治疗高度近视白内障患者安全可靠，对泪膜及角膜内皮细胞密度影响较小。

METHODS: From January 2016 to December 2016,38 cases(38 eyes)with high myopia and cataract were selected as study group, 24 males(24 eyes)and 14 females(14 eyes), average 65.2±2.37(60-72)years old. Age-related cataract patients without high myopia were as control group, 22 males(22 eyes)and 16 females(16 eyes), average 64.4±2.43(61-70)years old. The tear film and corneal endothelial cell density of the two groups were observed at 3, 7, 14d and 1mo after operations.

RESULTS: Between the two groups of preoperative SⅠt, BUT, FL, subjective rating, corneal endothelial cell density comparison, there were no statistically significant difference(P>0.05). In the two groups at 3, 7, 14d and 1mo after operations, BUT, FL, corneal endothelial cell density, subjective score comparison, the difference had statistical significance(P<0.01). Two groups after 3, 7, 14d comparative differences of SⅠt were statistically significant(P<0.01), not statistical significant at postoperative 1mo(P>0.05). At postoperative 3, 7, 14d, 1mo, FL, subjective rating, corneal endothelial cell density of the two groups were compared with preoperative, the difference was statistically significant(P<0.01).In the two groups at 3, 7, 14d after operation, SⅠt compared with the same group preoperative difference was statistically significant(P<0.01), no statistical significance when postoperative 1mo compared with preoperative(P>0.05). BUT of high myopia patients with age-related cataract surgery, at 3, 7, 14d and 1mo after operations decreased than preoperative, the difference was statistically significant(P<0.01). Age-related cataract patients without high myopia at 3, 7, 14d after operation decreased than preoperative, the difference was statistically significant(P<0.01), there was no statistically significant difference between preoperative and postoperative 1mo(P>0.05).

CONCLUSION: Phacoemulsification cataract surgery in the treatment of high myopia cataract patients is safe and reliable, and less influence on tear film and corneal endothelial cell density.