[关键词]
[摘要]
目的:对比Ahmed引流阀植入术和23G 532nm睫状体光凝术治疗外伤玻璃体切割术后继发性青光眼的临床疗效。
方法:选取2014-05/2016-01就诊于我院的外伤玻璃体切割术后继发性青光眼患者48例48眼,按随机数字表法分两组,对照组采用Ahmed引流阀植入术(25眼),试验组采用23G 532nm激光行睫状体光凝术(23眼)。比较两组患者的术后眼压控制率、角膜内皮细胞情况及相关并发症。
结果:术后3mo眼压控制率:试验组为83%(19/23),对照组为72%(18/25),差异无统计学意义(χ2=0.76,P=0.19)。术后1wk试验组并发症为39%(9/23),对照组并发症为68%(17/25),差异有统计学意义(χ2=4.02,P=0.03)。术后3mo,两组患者角膜内皮细胞密度均有下降,与术前比较差异有统计学意义(t=4.22,P<0.05); 两组之间角膜内皮细胞丢失率比较,试验组减少13%,对照组减少21%,无统计学差异(P>0.05)。
结论:Ahmed引流阀植入术和23G 532nm睫状体光凝术对于治疗外伤玻璃体切割术后继发性青光眼都能很好地控制眼压,手术相对较为安全,但23G 532nm睫状体光凝术更为经济实用,并发症更少。
[Key word]
[Abstract]
AIM: To compare the clinical efficacy of Ahmed drainage valve implantation and 23G cyclophotocoagulation for secondary glaucoma after traumatic vitrectomy.
METHODS: Totally 48 patients(48 eyes)with secondary glaucoma after traumatic vitrectomy were randomly selected from May 2014 to January 2016. According to the principle of random grouping, the patients were divided into experimental group and control group. Experimental group: 25 eyes were implanted with Ahmed drainage valve(25 eyes)and control group: 23G 532nm laser ciliary body photocoagulation(23 eyes). The intraocular pressure(IOP)and related complications were compared between the two groups.
RESULTS: The intraocular pressure control rate was 83%(19/23)in the experimental group and 72%(18/25)in the control group, the difference was no statistically significant(χ2=0.76, P=0.19). The postoperative complication rate was 39%(9/23)of experimental group at 1wk after operation. The overall complication rate in the control group was 68%(17/25), which was significantly higher than that in the experimental group(χ2=4.02,P=0.03). At postoperative 3mo, corneal endothelial cell density of two groups decreased, compared with the preoperative, the difference was statistically significant(t=4.22, P<0.05), that of experimental group decreased by 13%, control group by 21%, with no statistical difference(P>0.05).
CONCLUSION: Ahmed drainage valve implantation and 23G cyclophotocoagulation are safe for the treatment of secondary glaucoma after traumatic vitrectomy. The operation is relatively safe, but 23G cyclophotocoagulation is more effective, for economic and practical, fewer complications.
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[基金项目]
郴州市科技局科研基金资助项目(No.CZ2014032)