方法：回顾性分析。收集2014-01/2016-05于安徽医科大学第二附属医院确诊为开角型青光眼并行两种手术治疗的患者临床资料，统计患者的性别、年龄、手术前后视力、眼压、角膜内皮细胞计数及术后并发症的数据，并进行比较分析。

结果：Ex-press青光眼引流器与小梁切除术术后6mo视力比较无统计学差异(P>0.05)。两组患者术后眼压与术前相比均下降，差异有统计学意义(P<0.01)，但术后两组间各个时间点比较均无统计学差异。术后6mo，Ex-press青光眼引流器组角膜内皮细胞计数与术前比较无统计学差异(P>0.05)，而小梁切除术组存在统计学差异(P<0.05)。Ex-press青光眼引流器组术后并发症的发生率为15%，小梁切除术为43%，两组间并发症比较有统计学差异(P<0.05)。

结论：Ex-press青光眼引流器植入术与小梁切除术治疗开角型青光眼疗效相似，但前者对于角膜内皮的影响较小，且并发症发生率更低。

METHODS: We collected the clinical data of those patients who were diagnosed as open angle glaucoma and had undergone Ex-press glaucoma drainage device implantation or trabeculectomy in the Second Hospital of Anhui Medical University from January 2014 to May 2016. The data of patients was collected and used to make a comparison involving sex, ages, best corrected visual acuity(BCVA), intraocular pressure(IOP), the amount of corneal endothelium cells and complications before and after operations.

RESULTS: There was no significantly different(P>0.05)between the Ex-press group and trabeculectomy group on postoperative BCVA at 6mo. Both groups had obvious effects on the drop of IOP after operations(P<0.001), but there was no difference between the two groups at any time after operations. Ex-press group had no significant difference at 6mo while it had in the trabeculectomy group about the amount of corneal endothelium cells comparing with preoperative. The incidence rate of overall complications about Ex-press group and trabeculectomy group was 15% and 43% respectively, it had a significant difference between two groups(P<0.05).

CONCLUSION: The Ex-press glaucoma drainage device had similar efficacy with lower complication rate and smaller influence of corneal endothelium cells comparing with trabeculectomy.