方法：选择2013-05/2016-05我院接诊的白内障患者100例135眼，通过随机数表法分为观察组(50例68眼)和对照组(50例67眼)。观察组给予小切口手法碎核摘除+非球面人工晶状体植入，对照组给予超声乳化白内障摘除+非球面人工晶状体植入。比较两组患者手术效果。

结果：术后两组患者角膜内皮细胞计数均降低，与术前比较差异有统计学意义(P<0.05)，观察组在术后1、3mo时结果高于对照组，差异有统计学意义(P<0.05)； 观察组术后1mo时裸眼视力、最佳矫正视力优于对照组， 差异有统计学意义(P<0.05)，术后3mo时两组患者视力结果比较无统计学差异(P>0.05)； 术后1mo，观察组角膜散光高于对照组， 差异有统计学意义(P<0.05)，术后3mo时两组患者角膜散光结果比较无统计学差异(P>0.05)； 观察组在术中并发症、术后并发症总发生率均低于对照组，差异有统计学意义(P<0.05)。

结论：在白内障患者中应用手法碎核摘除术后植入非球面人工晶状体效果显著，可降低对角膜内皮细胞的损伤，并发症低，术后视力恢复良好。

METHODS: Totally 100 patients of cataract who received therapy from May 2013 to May 2016 in our hospital were selected. According to random number table, those patients were divided into the observation group(50 patients 68 eyes)and the control group(50 patients 67 eyes). The observation group was treated with small incision manual discectomy and aspheric intraocular lens implantation, the control group was treated with phacoemulsification cataract extraction and aspheric intraocular lens implantation, the operation effect of two groups were compared.

RESULTS: After operation, the corneal endothelial cell counts of the two groups decreased(P<0.05); in the observation group, the results were higher than those of the control group at 1 and 3mo after operation(P<0.05). In the observation group, the uncorrected visual acuity at 1mo after operation was better than that of the control group(P<0.05); there was no significant difference between the two groups in postoperative visual acuity after operation 3mo(P>0.05). At 1mo after surgery, the corneal astigmatism in the observation group was higher than that of the control group(P<0.05); there was no significant difference of corneal astigmatism between the two groups at 3mo after operation(P>0.05). The incidence of intraoperative complications and postoperative complications in the observation group were lower than that of the control group(P<0.05).

CONCLUSION: Aspheric intraocular lens implantation after manual nuclear fragmentation is well for cataract, which can reduce the damage to corneal endothelial cells, the complications rate is low and the postoperative visual acuity recovered well.