[关键词]
[摘要]
睫状神经营养因子(ciliary neurotrophic factor，CNTF)是神经保护因子中被研究的最多的因子之一，细胞包囊技术(encapsulated cell technology，ECT)为CNTF的临床应用提供了安全有效的给药途径。大量的研究证据表明，CNTF对视网膜色素变性、青光眼、年龄相关性黄斑变性、视神经损伤等眼部疾病具有神经保护作用。本文就CNTF与眼病的相关研究进展进行综述。
[Key word]
[Abstract]
Ciliary neurotrophic factor(CNTF)is one of the most studied neurotrophic factors. Encapsulated cell technology provides a safe and effective route for the clinical application of CNTF. A large body of evidence shows that CNTF has a neuroprotective effect on glaucoma, age-related macular degeneration, optic nerve injury and other eye diseases. This review focuses on the potential clinical application of CNTF in eye diseases.
[中图分类号]
[基金项目]
国家自然科学基金课题(No.81271026)
