方法：回顾性研究。收集22例32眼35～45岁过-9.00D的高度近视眼，对比3a前、3a后视盘、近视弧、脉络膜萎缩弧、近视弧种类、平均视网膜厚度和视网膜总体积的变化。

结果：经统计3年前、后视盘面积变化差异无统计学意义(t=0.95， P=0.35)； 3年后近视弧和脉络膜萎缩弧面积分别增加0.69±0.71mm²、0.57±0.97mm²，差异有统计学意义(t=-3.99， P=0.001； t=-2.33， P=0.03)。3年前、后近视弧种类、平均视网膜厚度和视网膜总体积变化差异无统计学意义(P>0.05)。

结论：大于-9.00DS的中青年高度近视患者三年主要改变指标是近视弧和脉络膜萎缩弧面积的增加，可作为临床随诊监测的形态学指标。

METHODS:A total of 22 HM patients(n=32 eyes, >-9 D), 35-45y, were enrolled in this self-controlled retrospective review. The following parameters were measured at baseline and 3-year follow-up visits: area of optic nerve head(ONH); area of peripapillary atrophy(PPA); area of peripapillary chorioretinal atrophy(PCA); type of PPA; average retinal thickness(ART); and total central retinal volume(TCRV).

RESULTS: There were no changes in the area of ONH(t=0.95, P=0.35)between baseline and 3-year follow-up visits. In contrast, the areas of PPA and PCA were significantly greater(0.69±0.71 and 0.57±0.97mm²,respectively)at the 3-year follow-up versus baseline(t=-3.99, P=0.001 and t=-2.33, P=0.03, respectively)visits. There were no changes in the type of the PPA. ART and TCRV did not differ significantly at the 3-year follow-up versus baseline visits(P>0.05).

CONCLUSION:Increased areas of PCA and PPA are the main fundus features of HM(>-9 D)in young adults. PPA and PCA should be important morphological parameters during follow-up for HM in clinic.