方法：收集北京爱尔英智眼科医院2014-10/2016-10门诊就诊的原发性开角型青光眼患者和同期正常对照者。所有受试者均进行眼科常规前节、眼底检查，压平眼压测量，Humphery 24-Ⅱ中央30°视野检查，Topcon OCT行视盘神经纤维层厚度和黄斑区节细胞复合体(GCC)检查及柯谛亚电生理仪分离格栅模式定性检查。 计算Ic-VEP诊断原发性开角型青光眼的敏感性、特异性和ROC曲线下面积。

结果：Ic-VEP 检测原发性开角型青光眼的敏感性为82%， 特异性为92%，ROC曲线下面积为0.872。Ic-VEP与中期青光眼患眼黄斑区节细胞复合体(GCC)损害的一致性较好(Kappa值=0.75)。

结论：Ic-VEP是一种新型的诊断早中期青光眼的有效指标。

METHODS: All the participants included glaucoma patients and normal people came from Beijing Aier-Intech Eye Hospital from October 2014 to October 2016. All the participants performed slit lamp examination, fundus examination, Goldmann applanation tonometer, Humphery visual field examination, retinal nerve fiber layer(RNFL)thickness and macular ganglion cell complex(GCC)thickness examination and Ic-VEP. The sensitivity and specificity of Ic-VEP in diagnose of glaucoma were main results.

RESULTS: The sensitivity and specificity of Ic-VEP in diagnose of glaucoma is 82% and 92% respectively. The area under ROC curve was 0.872. Consistency of Ic-VEP and GCC thickness in moderate glaucoma was good(Kappa value=0.75).

CONCLUSION: Ic-VEP is a useful new method for the diagnosis of early and middle stage glaucoma.